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NIH Research Festival 2012 Program - Research Festival - National ...

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Concurrent Symposia Session II<br />

Natcher Conference Center<br />

Conference Room F<br />

<strong>NIH</strong> Translational <strong>Research</strong> Interest Group<br />

Health disparities: Advances in translational,<br />

clinical, and population sciences<br />

Co-Chairs: Anil Wali, NCI; and Jeffrey Kopp, NIDDK<br />

Health Disparities are differences in health outcomes among population groups that reflect<br />

socio-economical, geographical and racial/ethnic inequalities. Biological, environmental<br />

and behavioral factors can lead to unequal disease burden in prevalence, incidence<br />

and mortality rates seen among medically underserved and vulnerable populations.<br />

This symposium is timely to take stock of implications of these factors on various<br />

disease manifestations and outcomes, and provide insights on the latest advances in<br />

combating them with high-throughput medical technologies. The symposium topic is<br />

of broad interest to <strong>NIH</strong> intramural investigators who are engaged in various aspects<br />

of trans-disciplinary efforts to understand the molecular basis of linkages between<br />

obesity, metabolomics, epigentics in population based studies. This symposium will<br />

serve as a scientific platform to exchange state-of-the-art information on racial/ethnic<br />

differences encountered in the translational setup from bench to bedside, and how<br />

these experimental approaches could improve the early detection, prevention and<br />

therapeutic strategies applicable to the communities.<br />

Cheryl Winkler, NCI<br />

Identification of APOL1 genetic variation explains much of the increased chronic<br />

kidney disease characteristic of African Americans<br />

Stefan Ambs, NCI<br />

A prognostic metabolome signature in breast tumors is linked to a distinct DNA<br />

methylation pattern in African-American and European-American patients<br />

Kevin Gardner, NCI<br />

Molecular Linkages between race, obesity and triple-negative breast cancer<br />

Charles Rotimi, NHGRI<br />

Ethnic differences in lipid distribution: Implications for disease risk and<br />

response to treatment<br />

Cristina Rabadan-Diehl, NHLBI<br />

Health disparities in cardiovascular disease: A global health perspective<br />

Wednesday, October 10, <strong>2012</strong><br />

10:00 a.m.–Noon<br />

31

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