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NIH Research Festival 2012 Program - Research Festival - National ...

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Concurrent Symposia Session III<br />

Natcher Conference Center<br />

Conference Room E1/E2<br />

Imaging traumatic brain injury:<br />

Challenges and solutions<br />

Co-chairs: Amir H. Gandjbakhche, NICHD; and<br />

Paul Smith, NIBIB<br />

Wednesday, October 10, <strong>2012</strong><br />

2:00 p.m.–4:00 p.m.<br />

Approximately 1.7 million people sustain a traumatic brain injury annually. 300,000<br />

veterans in Iraq/Afghanistan wars experienced TBI, mostly mild. Injuries range from<br />

severe structural damages detected in (MRI/CT) imaging, to those injuries which exhibit<br />

normal structural imaging but manifest different levels of cognitive deficits such as memory<br />

problems, reduced attention, inability to concentrate on a single task. The poor quality<br />

of life associated with TBI, create severe morbidities in all aspects of patient life (family,<br />

work, and society), and cost billions of dollars. Accurate diagnosis and classification<br />

of TBI are becoming a critical need for personalized therapy. However, phenotyping<br />

TBI is still a huge challenge. Imaging methods, both structural and functional, could<br />

play an important role for phenotype classification. In this symposium we will address<br />

the role of imaging techniques for TBI diagnosis and therapy.<br />

James Smirniotopoulos, USUHS<br />

Imaging TBI: Known knowns and unknown unknowns<br />

Ramon Diaz-Arrastia, USUHS<br />

Endophenotypes of traumatic brain injury: Implications for the next generation<br />

of clinical trials<br />

Lawrence Latour, NINDS<br />

The CNRM traumatic head injury neuroimaging classification (THINC) study:<br />

Steps toward the objective diagnosis and classification of TBI<br />

Amir Gandjbakhche, NICHD<br />

Imaging cognitive function with near infrared spectroscopy for TBI diagnosis<br />

Emily Wood, NINDS<br />

Detecting axonal degeneration in multiple sclerosis with diffusion weighted spectroscopy<br />

FARE Award Winner<br />

49

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