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ALTERACIONES DEL CICLO DE LA UREA CON

ALTERACIONES DEL CICLO DE LA UREA CON

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Alteraciones del ciclo de la urea: deficiencia del enzima OTC<br />

Ammonul Dosage and Administration Summary Tables<br />

Patient Population: Older Children and Adults: NAGS, CPS and OTC Deficiency<br />

Components of Infusion Solution<br />

Dosage Provided<br />

Ammonul<br />

Arginine<br />

HCl<br />

Injection,<br />

10%<br />

Dextrose<br />

Injection,<br />

10%<br />

Sodium<br />

Phenylacet<br />

ate<br />

Sodium<br />

Benzoate<br />

Arginine<br />

HCl<br />

Loading<br />

Dose (90<br />

min)<br />

55 mL/m 2 2.0 mL/kg greater or<br />

equal to 25<br />

mL/kg<br />

5.5 g/m 2 5.5 g/m 2 200 mg/kg<br />

Maintenanc<br />

e Dose<br />

55 mL/m 2<br />

/24 hr<br />

2.0<br />

mL/kg/24 hr<br />

greater or<br />

equal to 25<br />

mL/kg<br />

5.5 g/m 2<br />

/24 hr<br />

5.5 g/m 2<br />

/24 hr<br />

200<br />

mg/kg/24 hr

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