Extended-Spectrum Beta-Lactamasen (ESBL) - Paul Ehrlich ...

Deutschland: ESBL in nosokomialen E. coli
Antibiotikaresistenz-Surveillance (ARS): ESBL-Projekt 2008
2004 2008
no. of strains n = 49 no. of strains n = 154
no. of hospitals n = 29 no. of hospitals n = 150
TEM type n = 7 TEM type n = 6
SHV type n = 2 SHV type n = 3
CTX-M type n = 40 (81 %) CTX-M type n = 143 (93 %)
CTX-M-1 n = 10 CTX-M-1 n = 50
CTX-M-2 n = 2 CTX-M-2 n = 4
CTX-M-3 n = 7 CTX-M-3 n = 1
CTX-M-9 n = 7 CTX-M-9 n = 2
CTX-M-14 n = 2 CTX-M-14 n = 10
CTX-M-15 n = 11 (27,5%) CTX-M-15 n = 76 (53 %)
ca. 70-80% aller ESBL Isolate resistent gegen Sulfonamide und Fluorchinolone