Wien, 28 - Repository of the LBI-HTA - Ludwig Boltzmann Gesellschaft
Wien, 28 - Repository of the LBI-HTA - Ludwig Boltzmann Gesellschaft
Wien, 28 - Repository of the LBI-HTA - Ludwig Boltzmann Gesellschaft
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DatenextraktionTabelle 4.1-4: Results from case studies on radi<strong>of</strong>requency ablation for <strong>the</strong> treatment <strong>of</strong> metastases <strong>of</strong> <strong>the</strong>adrenal glandAuthor, year, reference number Carrafiello (2010) [21]CountrySponsorInterventionProductMonitoring systemRF-GeneratorElectrodeComparatorStudy designNumber <strong>of</strong> patientsITn/aRFA4 patients: CT; Light Speed Plus R (GE Medical Systems); Aquilon 64 (Toshiba)2 patients: US; Technos MPW ( Esaote)RF 3000 (Boston Scientific)Coaxial LeVeen (Boston Scientific)noprospective case series6 (with 6 adrenal metastases)Age <strong>of</strong> patients (years) O/ 67 (range 55-74)Sex <strong>of</strong> patients (M/F) 2 / 4Size <strong>of</strong> metastasis (cm) O/ 2.9 (range 1.5-4.0)Indicationinoperable, adrenal metastasesNumber <strong>of</strong> RFA sessions in number<strong>of</strong> patients1 in 5 patients (83.3%), 2 in 1 patient (16.7%)Incomplete ablation sessions 0 (=0%)Follow up (months) O/ 21 (range 6-36)Drop-out rate 0 (=0%)OutcomeEfficacySurvivaln/aRecurrence 1/6 (16.7%)SafetyPost-interventional (minor) morbidityHypertensive crisis 1 (16.7%)Mortalityn/aProcedure-related mortality n/aoverall: 2 (33.3%)pain and fever (post-RFA): 1 (16.7%)hypertension (post-RFA): 1 (16.7%)CT: computed tomography; M/F: male/female; n/a: not available; RF: radi<strong>of</strong>requency; RFA: radi<strong>of</strong>requency ablation;US: ultrasound<strong>LBI</strong>-<strong>HTA</strong> | 2012 29
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