Wien, 28 - Repository of the LBI-HTA - Ludwig Boltzmann Gesellschaft
Wien, 28 - Repository of the LBI-HTA - Ludwig Boltzmann Gesellschaft
Wien, 28 - Repository of the LBI-HTA - Ludwig Boltzmann Gesellschaft
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Radi<strong>of</strong>requenzablation bei benignen und malignen Vera¨nderungen endokriner OrganeTabelle 5-1: Evidence pr<strong>of</strong>ile: efficacy and safety <strong>of</strong> radi<strong>of</strong>requency ablation for benign thyroid nodulesNo <strong>of</strong> studies/patientsDesign Limitations Consistency <strong>of</strong>results2/46 case series serious limitations some inconsistencyDirectness Effect size* low incidence, lack <strong>of</strong> precise data, sparse data, strong or very strong association, high risk <strong>of</strong> publication bias, dose-efficacy gradient, residual confounding plausibleEfficacyOutcome: symptoms (pressure)O<strong>the</strong>r modifyingfactors*direct 10-point scale: O/ 5.2 at enrolment; O/ 1.8 after 6 months (-3.4); p
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