ACHEMA Daily 2022 #2

44
ACHEMA DAILY #2 | TUESDAY, AUGUST 23, 2022
Lab/Pharma/Packaging
Mechanical Separation
Single-use Pharmaceutical Separators
The Kytero Single Use Pharma Separator
Source: GEA Group
Launched in the fall of 2021,
the Kytero Single-Use Pharma
Separator has already struck a
chord with research institutes
and companies in the pharmaceutical
industry. Kytero stands
for maximum separation efficiency
with extremely gentle
product handling and creates
new ways for processing cellculture-based
fermentations
with a yield of 98 % and more.
This type of technology is in
high demand for pilot plants,
university laboratories and
small-scale production by
biopharmaceutical manufacturers
worldwide, as it relies on
the well-established technology
of disk separators. The use
of filtration technology can
thus be significantly reduced.
The Kytero 500 was developed
for a capacity of up to 150 l/h
and is thus suitable for laboratories
and small batches. For
reliable scale-up, another
model will follow in the short
term. The basis for the development
work was the well-established
stainless-steel pharmaceutical
disk separator technology.
The The proven GEA
feed system guarantees particularly
gentle product treatment,
and the vitality of shearsensitive
products is preserved.
Product runs and scientific
tests at the ZHAW School of Engineering
in Zurich have confirmed
this.
In centrifugation, unlike filtration,
the separation of the
medium is not achieved by
filter media (filter plates and
filter cloths), but by utilizing
the centrifugal force that occurs
in conjunction with a disc
stack for increased clarification
efficiency. The mobile „Plug &
Produce“ unit with a minimal
footprint fits easily into any
production room. With the
single-use separator, all product-contacting
parts are replaced
after use, preventing
any cross-contamination without
the need for cleaning and
sterilization. The frictionless
drive system provides 100 %
biocontainment by eliminating
the need for seals or mechanical
bearings. Set-up and
changeover time is minimal at
only 5 to 10 min. No auxiliary
equipment such as water,
buffers, or tanks is required.
The noise level is very low at
less than 69 dBA. The temperature
increase of the product,
which is unavoidable during
centrifugation, is minimal at
less than two degrees. dl
GEA Group
Hall 4.0, Stand G66
Schutzart IP69K
Servogetriebemotoren aus Edelstahl
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Die Antriebe sind mit einer
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sind resistent
gegen Heißdampf und korrosive
Reinigungsmittel, zwei typische
Anforderungen gerade bei
CIP- und SIP-Abläufen. Die
Schutzart der Motoren, die sich
flexibel auch in vorhandene
Maschinenkonstruktionen integrieren
lassen, beträgt IP 69K.
Die Servogetriebemotoren sind
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Bild: SEW-Eurodrive