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The European Pharmaceutical Wholesale Industry: - phagro

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<strong>The</strong> <strong>European</strong> <strong>Pharmaceutical</strong> <strong>Wholesale</strong> <strong>Industry</strong><br />

4.2.1 Influencing Factors on <strong>Wholesale</strong>rs’ Sales<br />

<strong>Pharmaceutical</strong> market growth, and therefore the wholesale industry’s competitiveness,<br />

is influenced by a set of different interacting factors, as represented in<br />

Table 3.<br />

Table 3: Factors influencing <strong>Pharmaceutical</strong> <strong>Wholesale</strong>rs’ Sales<br />

Factor Trend<br />

Development of prices for “old” pharmaceuticals 5 Falling<br />

Development of prices for “new” pharmaceuticals Steep increase<br />

Line extension (product diversification) Not assessable<br />

Structural changes Not assessable<br />

Development of margins 6 Falling<br />

Quantity of consumption Slow increase<br />

Share of non-pharmaceutical products Increase<br />

Mail order systems, direct delivery Increase<br />

Source: IPF, IMS Health<br />

<strong>The</strong> first four factors, the so-called elements of growth (IMS Health), measure the<br />

impact of changes in prices of products launched in the market before the base<br />

period, the impact of line extensions and the impact of structural changes on<br />

pharmaceutical sales. <strong>The</strong> effects of the launch of new molecular entities and metoo<br />

products on pharmaceuticals’ sales are documented by the development of<br />

prices of new pharmaceuticals. <strong>The</strong> following sections will refer to these elements<br />

of growth in more detail.<br />

New pharmaceuticals<br />

(except line extensions)<br />

New molecular<br />

entities<br />

Me-too products<br />

Figure 13: Elements of Growth<br />

2004 (base date)<br />

Old pharmaceuticals<br />

New pharmaceuticals 2003<br />

New pharmaceuticals 2002<br />

New pharmaceuticals 2001<br />

...<br />

...<br />

...<br />

Source: IMS Health, IPF<br />

Price changes<br />

Line extensions<br />

Structural changes<br />

5 It may be observed that in some countries a price-index of ex-factory prices exhibits a<br />

flat, if no negative development. In any case, it is significantly lower than the development<br />

of the consumer-price index.<br />

6 <strong>The</strong> terms mark-up and margin are often used similarly. However, the mark-up is calculated<br />

on basis of the ex-factory price (bottom-up calculation), whereas margins denote<br />

the spread between the ex-factory price and the pharmacy purchase price (top-down calculation).<br />

IPF Institute for Pharmaeconomic Research 18

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