Understanding Clinical Trial Design - Research Advocacy Network

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UNDERSTANDING CLINICAL TRIAL DESIGN: A TUTORIAL FOR RESEARCH ADVOCATES Judicial Inference Example It may be helpful to compare statistical inference used in hypothesis testing to the judicial inference process involved in criminal trials. The presumption that the defendant is innocent until proven guilty is equivalent to the null hypothesis. Requiring “evidence beyond a reasonable doubt” to convict a defendant is aimed at minimizing the chances of convicting innocent defendants. This is akin to minimizing type I errors (α
22 UNDERSTANDING CLINICAL TRIAL DESIGN: A TUTORIAL FOR RESEARCH ADVOCATES
Page 1 and 2: Understanding Clinical Trial Design
Page 3 and 4: UNDERSTANDING CLINICAL TRIAL DESIGN
Page 13 and 14: 12 Concept Development Example UNDE
Page 15 and 16: 14 Confounding Example UNDERSTANDIN
Page 17 and 18: 16 Stratification Example Consider
Page 19 and 20: 18 Statistical Inference Example UN
Page 21: 20 UNDERSTANDING CLINICAL TRIAL DES
Page 25 and 26: 24 UNDERSTANDING CLINICAL TRIAL DES
Page 27 and 28: 26 Bayesian Clinical Trial Example
Page 29 and 30: 28 Adaptive Method Example Adaptati
Page 31 and 32: 30 Figure 14. Patient Allocation Ad
Page 33 and 34: 32 Patient Enrichment Example UNDER
Page 37 and 38: 36 VI. Acknowledgements UNDERSTANDI
Page 39 and 40: 38 VIII. Glossary UNDERSTANDING CLI
Page 53: 52 UNDERSTANDING CLINICAL TRIAL DES

Understanding Clinical Trial Design - Research Advocacy Network

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