2012 - Europe Direct Iasi

EUROINVENT 2012
research border areas (cosmetogenomics, proteomics, etc) has as
consequence the better understanding of skin ageing induced
changes and to validate the efficacy of cosmetic ingredients.
Based on this depth characterization, Biotehnos
Laboratories have developed from three Romanian medicinal
plants, new anti-ageing active ingredients, targeting different
aspects of this phenomena: restoring the fibril organization in
superficial wound healing (saponozidic compound from
Callendula Officinalis), estrogen-like action (bioactive
complexes from Trifolium pratense and Trigonella
foenumgraecum), photo protective effect, counteracting the
cellular damages induced by UV-A and UV-B radiation ( a
phyto-complex from Trigonella foenumgraecum).
All these vegetal ingredients are selective extracts and
purified substances with a specific design in order to interact
with the cellular / molecular target, produced through new
technologies based on the fully capitalization of vegetal raw
materials. The starting process is the ecologic growing of plants,
followed by selective extraction in steps and separation of active
components, ending with the recycling of the vegetal waste as
provender for animals or organic fertilizer.
Cellular and genomic research for the ingredients
design, together with the fully exploitation of vegetal raw
material through advanced technologies will assure a positive
impact on the quality of the new products.
Research activities were done during Dermolab project, with
financial contribution from European Union (POS CCE ID 383
SMIS CSNR 6009 CTR 107/2010).
4.17.
Title
Antineoplastic clavinic alkaloid type product of veterinary use
and preparation process thereof
Craita Maria ROSU, Pincu ROTINBERG, Zenovia OLTEANU,
Stefania SURDU, Elena TRUTA, Cosmin Teodor MIHAI,
Authors Luminita HRITCU, Daniela GHERGHEL, Monica
Institution
HANCIANU, Anca MIRON, Ana Clara APROTOSOAIE, Oana
CIOANCA
Institute of Biological Research Iasi – branch of INCDSB
Bucuresti
„Alexandru Ioan Cuza” University of Iasi
“Ion Ionescu de la Brad” University of Agricultural Sciences and
Veterinary Medicine of Iasi
“ Gr. T.Popa” University of Medicine and Pharmacy of Iasi
Patent no. Patent application No. A/01301 / 5.12.2011
Description The invention proposes a new bioproduct of clavinic alkaloid
type, extracted and purified from Claviceps purpurea fungus, as
Class 4
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