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Respiratory System Disorders and Therapy From a New - Louis Bolk ...

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dissolution. These diversions can lead to two different types of pathological processes when<br />

the imbalance is not corrected. The inflammation phase also has two types of diversion.<br />

An example of the consolidating type is any chronic inflammatory process; an example of<br />

the dissolving type is an infection, such as in an infected wound or in pneumonia.<br />

Inflammation<br />

Dissolution Consolidation<br />

Fig. 2.4. The diversion in the inflammatory phase<br />

Two types of cells are especially active in the inflammation phase: The macrophages <strong>and</strong><br />

the neutrophils. The leading impulse in the inflammatory phase is to restore the impaired<br />

connection with the rest of the organism with the aid of forces that can be described as<br />

interactive in nature <strong>and</strong> that function alongside the integrative forces that move the<br />

healing process along to completion (Bie et al 2008, Ch. 3).<br />

The four characteristic signs of inflammation are rubor, calor, dolor, <strong>and</strong> tumor. In chronic<br />

inflammatory disease, we see a preponderance of swelling <strong>and</strong> reddening of tissues<br />

together with pain sensations. In infectious processes, warmth in the form of fever is<br />

additionally present <strong>and</strong> the dominant symptom.<br />

2.4.3. The Pathological Diversion of Asthma<br />

In chronic asthma <strong>and</strong> its exacerbations, the pathological findings show characteristics of<br />

persistence of inflammatory processes:<br />

• The thickening <strong>and</strong> remodeling of the airways <strong>and</strong> the characteristic exudate are<br />

constant phenomena that show the consolidation in asthma hindering normal<br />

breathing movements <strong>and</strong> averting the completion of the healing process<br />

• The “slowing down” of the inflammation phase leads to chronicity. There is delayed

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