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Respiratory System Disorders and Therapy From a New - Louis Bolk ...

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Table 2.1. Pathophysiological characteristics of chronic asthma <strong>and</strong> exacerbations<br />

Pathophysiology of ASTHMA particularly in exacerbations<br />

Reaction to stimuli Hyperreactive airways<br />

Consolidating tendency Airway remodeling<br />

Dissolving tendency Delayed resolution of the inflammation phase<br />

2.4.4. The Pathological Diversion of Pneumonia<br />

In an uncomplicated pneumonia, the healing process is eventually completed, it does not<br />

become permanently stuck, it is temporarily diverted. However, in pneumonia, the inflammation<br />

phase is intensified <strong>and</strong> prolonged, compared to a normal healing process when there is no<br />

infection. The natural responsiveness to stimuli is used up onesidedly in the infection. <strong>New</strong><br />

stimuli will meet with a reduced ability to respond, such as we see in complicated infections.<br />

Pneumonia:<br />

The acute phase of<br />

inflammation<br />

persists<br />

due to infection<br />

Acute phase reaction/<br />

Hemostasis<br />

Proliferation<br />

Maturation<br />

Infection/Injury Completion of healing process<br />

Fig. 2.6. Dynamic diagram of the diversion of the healing process in pneumonia

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