04.03.2013 Views

Respiratory System Disorders and Therapy From a New - Louis Bolk ...

Respiratory System Disorders and Therapy From a New - Louis Bolk ...

Respiratory System Disorders and Therapy From a New - Louis Bolk ...

SHOW MORE
SHOW LESS

Create successful ePaper yourself

Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.

esolution of the inflammation. There is a lack of dissolving impulse to balance the<br />

consolidation. There is, for instance, no fever which could help break up the chronic<br />

inflammation (see fig.2.5.)<br />

• <strong>From</strong> immunology, we know that the organism is not able to stop the inflammatory<br />

reaction in asthma (Companion Immunology, Bie 2006). There is an overreaction to<br />

stimuli in the lower respiratory tract: hyperreactivity.<br />

Asthma:<br />

The inflammation<br />

phase persists<br />

<strong>and</strong> leads to chronic<br />

inflammation<br />

(allergic <strong>and</strong> aspecific)<br />

Acute phase reaction/<br />

Hemostasis<br />

Proliferation<br />

Maturation<br />

Infection/Injury Completion of healing process<br />

Fig. 2.5. Dynamic diagram of the diversion of the healing process in asthma<br />

Conclusion<br />

The pathophysiology of asthma attacks shows persistence of the inflammatory phase of<br />

the general healing process leading to a chronic inflammatory disease with:<br />

1. Hyperreactivity<br />

2. Consolidation<br />

3. A lack of resolution.<br />

<strong>Bolk</strong>’s Companions RespiRatoRy system DisoRDeRs anD theRapy - 23

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!