Cambridge Pre-U Syllabus - Cambridge International Examinations

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16 1.1 Eukaryotic cell structure Content Microscopy Cell membranes Organelles: structure and function Cambridge Pre-U Draft Learning outcomes Candidates should be able to: a) explain the relative advantages of light and electron microscopes (including the theoretical basis for these relative advantages) b) explain and distinguish between resolution and magnification with reference to light microscopy and electron microscopy c) discuss the importance of cell surface membranes in defining cells, as a characteristic of all living things and the extent to which they appear to be essential for life d) describe and explain the fluid mosaic model e) discuss the roles of membrane proteins including transporters (channels and carriers [including CFTR]), pumps, receptors and antigens f) describe the factors affecting the permeability and fluidity of membranes g) explain how and why different substances move across membranes (including simple and facilitated diffusion, osmosis, active transport, endocytosis (phagocytosis and pinocytosis) exocytosis,(secretory pathway) h) recognise the following cell organelles and describe their functions • nucleus • nuclear envelope • nucleolus • rough and smooth endoplasmic reticulum • ribosomes • Golgi apparatus • lysosomes • secretory vesicles • proteasomes • mitochondria • chloroplasts • vacuoles • cell walls • centrioles • cilia and flagella
Cambridge Pre-U Syllabus Practical learning outcomes Candidates should be able to: i) use a light microscope, stage micrometer scale and eyepiece graticule ii) correctly measure, using a light microscope and specimens, the size of objects and calculate their magnification iii) produce drawings of an organism, a section through a small organism and a part of an organism as seen under the light microscope iv) produce correctly labelled and annotated drawings of cells from microscopic examination and from electronmicrographs v) recognise organelles in a variety of cells from across the four eukaryotic kingdoms vi) investigate the movement of materials through cell membranes, for example by diffusion, osmosis and active transport vii) estimate the water potential of a plant tissue by investigating the change in length or mass of suitable plant tissue viii) estimate the solute potential of plant cells using percentage plasmolysis of suitable plant epidermal cells ix) investigate the effect of temperature and different solvents on the permeability of membranes x) investigate endocytosis and intracellular digestion in a protoctist, such as Paramecium or Vorticella, or using yeast stained with neutral red 1.2 Prokaryotic cells Content Structure of prokaryotic cells Pathogenic bacteria Antibiotics Reproduction Learning outcomes Candidates should be able to: a) outline key structural features of prokaryotic cells (including: unicellular, 1-5 µm diameter, peptidoglycan cell walls, lack of membrane-bound organelles, naked circular DNA, 70S ribosomes) b) outline the structure and functions of bacterial ribosomes and cell walls and the significance of the structure of bacterial cell walls for the use of antibiotics c) explain the mode of transmission and infection of bacterial pathogens (including Agrobacterium tumefaciens (Rhizobium radiobacter), Clostridium tetani, Mycobacterium tuberculosis and Helicobacter pylori) d) explain the mode of action of penicillin on bacteria (as an example of an antibiotic) and explain why penicillin does not affect viruses e) outline the mechanism of asexual reproduction by binary fission in a typical prokaryote Practical learning outcomes Candidates should be able to: i) investigate Gram staining of bacterial cell walls ii) investigate the effect of penicillin or other antibiotics on bacterial growth (e.g. by use of Mast Rings) 17
Page 1: Cambridge Pre-U Syllabus - DRAFT Su
Page 4 and 5: 2 © University of Cambridge Intern
Page 6 and 7: 4 Introduction Cambridge Pre-U Draf
Page 8 and 9: 6 Aims The course aims to: Cambridg
Page 10 and 11: 8 Assessment objectives Cambridge P
Page 12 and 13: 10 Description of Papers Cambridge
Page 14 and 15: 12 Curriculum Content The syllabus
Page 16 and 17: 14 Cambridge Pre-U Draft In the con
Page 20 and 21: 18 1.3 Cell replication Content DNA
Page 22 and 23: 20 1.5 Respiration Content ATP Chem
Page 24 and 25: 22 Cambridge Pre-U Draft Practical
Page 26 and 27: 24 2. THE ORIGIN AND EVOLUTION OF L
Page 28 and 29: 26 2.3 The evolution of life Conten
Page 30 and 31: 28 3. ANIMAL PHYSIOLOGY Section 3 (
Page 32 and 33: 30 3.3 Nerves, muscles and behaviou
Page 34 and 35: 32 3.5 The immune system Content St
Page 36 and 37: 34 4. THE LIFE OF PLANTS Cambridge
Page 38 and 39: 36 4.3 Reproduction Content Pollina
Page 40 and 41: 38 5. ENVIRONMENTAL STUDIES Cambrid
Page 42 and 43: 40 5.2 Measuring and conserving bio
Page 44 and 45: 42 Cambridge Pre-U Draft Section A
Page 46 and 47: 44 Assessment of skills in Componen
Page 48 and 49: 46 Cambridge Pre-U Draft Candidates
Page 50 and 51: 48 Cambridge Pre-U Draft Sub-skill
Page 56 and 57: 54 Cambridge Pre-U Draft Skill Area
Page 58 and 59: 56 Cambridge Pre-U Draft Laboratory
Page 60 and 61: 58 Cambridge Pre-U Draft Reagents,
Page 62 and 63: 60 Appendix 2: Textbooks and IT res
Page 64 and 65: 62 Cambridge Pre-U Draft Biology Pr
Page 66 and 67: 64 Notes on the use of statistics i
Page 68 and 69:
66 Cambridge Pre-U Draft Glossary o
Page 70 and 71:
68 Appendix 4: Performance Descript
Page 72 and 73:
70 Appendix 5: Additional informati
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72 Cambridge Pre-U Draft
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Cambridge Pre-U Syllabus - Cambridge International Examinations

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