Colposcopy and Programme Management - Cytology Training Centre

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More other biomarkers • Brn-3a mRNA indicates activation of E6/7 as transcription factor. • Ki-67, PCNA, HTERT unreliable. • Advantage of biomarker panels when added to cytology is results could alter cytologic diagnosis – eg borderline grades re-classified normal, low or high grade – HPV testing unable to alter cytologic result. • P63, Nuf-2, miRNA’s candidate biomarkers • Biomarkers may have role in screening/ triage.
Summary • General tidying up • Benign endometrial cells in cervical samples • DES exposure • Cytology sampling at 1 st visit • MDT meetings • Advice to women • Follow up after treatment • Post hysterectomy management • Management after early stage cancer • Withdrawal from screening • Role of HPV testing • Screening interval unchanged • Overall a few more standards
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Colposcopy and Programme Management
Page 3 and 4: • No change to any data items req
Page 5 and 6: In general • No planned change to
Page 7 and 8: Diagnosis and management of cGIN
Page 9 and 10: In general (continued) Invasive dis
Page 11 and 12: In general (continued) Follow up
Page 13 and 14: In general (continued) Clinic staff
Page 15 and 16: In general (continued) • All colp
Page 17 and 18: Benign endometrial cells (continued
Page 19 and 20: Cervical screening for women expose
Page 21 and 22: Cervical cytology should not be rep
Page 23 and 24: Multidisciplinary team meetings •
Page 25 and 26: Frequency of MDT meetings • MDT s
Page 27 and 28: Information given to patients follo
Page 29 and 30: Follow-up for women after treatment
Page 31 and 32: Follow-up for women after treatment
Page 33 and 34: Follow up after hysterectomy (conti
Page 35 and 36: Follow up after hysterectomy (conti
Page 37 and 38: Management for women following trea
Page 39 and 40: Where does HPV testing fit into the
Page 41 and 42: HPV testing to triage low-grade abn
Page 43 and 44: HPV testing to triage low-grade abn
Page 45 and 46: 12 responses Austria, Belgium, Croa
Page 47 and 48: Beyond No 20 - European picture 200
Page 49 and 50: Recurrent inad cytology HPV test 12
Page 51 and 52: But… • HPV types in the UK chan
Page 53: • CDC6 - cell division cycle prot
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Colposcopy and Programme Management - Cytology Training Centre

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