Antiemetics for reducing vomiting related to acute ... - Update Software

D A T A A N D A N A L Y S E S
Comparison 1. Oral ondansetron (weight dependent dose) vs placebo
Outcome or subgroup title
No. of
studies
No. of
participants Statistical method Effect size
1 Rate of admission to hospital
(during ED stay)
3 465 Risk Ratio (M-H, Fixed, 95% CI) 0.40 [0.19, 0.83]
2 Rate of admission to hospital (up
to 72 hrs following discharge
from ED stay) best-worst case
scenario
3 461 Risk Ratio (M-H, Fixed, 95% CI) 0.60 [0.34, 1.04]
3 Rate of admission to hospital (up
to 72 hrs following discharge
from ED stay) worst-best case
scenario
3 461 Risk Ratio (M-H, Fixed, 95% CI) 0.73 [0.43, 1.22]
4 Rate of intravenous rehydration
(during ED stay)
3 465 Risk Ratio (M-H, Fixed, 95% CI) 0.41 [0.29, 0.59]
5 Rate of intravenous rehydration
(up to 72 hrs following
discharge from the ED stay),
best-worst case scenario
3 461 Risk Ratio (M-H, Fixed, 95% CI) 0.52 [0.38, 0.71]
6 Rate of intravenous rehydration
(up to 72 hrs following
discharge from the ED stay),
worst-best case scenario
3 461 Risk Ratio (M-H, Fixed, 95% CI) 0.57 [0.42, 0.76]
7 Proportion of participants with
cessation of vomiting
3 465 Risk Ratio (M-H, Fixed, 95% CI) 1.33 [1.19, 1.49]
8 Revisit rate 3 457 Risk Ratio (M-H, Fixed, 95% CI) 1.09 [0.66, 1.79]
Antiemetics for reducing vomiting related to acute gastroenteritis in children and adolescents (Review)
Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.
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