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Databases and Systems

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138<br />

Painting:<br />

An alternative mean of defining the domain is for the user to delineate or paint the<br />

new domain directly onto the reconstruction using the Edinburgh Mouse Atlas paint<br />

program (MAPaint see figure 5) or equivalent software [9]. This allows the user to<br />

select an arbitrary section <strong>and</strong> delineate regions directly using a variety of painting<br />

“tools” [9]. This program also allows the editing of domains defined by any other<br />

means therefore can be used in conjunction with a text definition of the domain to<br />

allow additional refinement. This is likely to be more efficient than defining the<br />

whole 3D domain de novo.<br />

Figure 5: The main feedback window <strong>and</strong> two section views of the Edinburgh Mouse<br />

Atlas Theiler stage 14 embryo in the program MAPaint showing the 3D feedback <strong>and</strong><br />

view controls.<br />

Warping:<br />

Submission using text <strong>and</strong>/or painting can be time consuming <strong>and</strong> most graphical<br />

data will be entered by using image processing both to extract the required pattern<br />

<strong>and</strong> to transform or warp the data onto the atlas. Before generating the submission it<br />

is assumed that the user has digitized the required experimental data, then the<br />

simplest means is to locate the matching section from the atlas <strong>and</strong> for the user to<br />

define “tie-points’’ that can be used to produce a warp transformation, e.g. as a thin-

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