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Databases and Systems

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291<br />

Genome Research <strong>and</strong> are beginning to use the current systems for projects there <strong>and</strong><br />

elsewhere. Though the software is incomplete in many ways, it is proven technology<br />

that in our h<strong>and</strong>s, at least, greatly reduces the work of creating laboratory informatics<br />

systems.<br />

While we welcome others to use our software, we believe there is greater value in<br />

the ideas. The total quantity of code is modest, comprising about 10,000 lines of<br />

Perl5. It would not be hard to reproduce the ideas in other contexts, <strong>and</strong> we<br />

encourage others to do so.<br />

References<br />

1. Sargent, R., D. Fuhrman, T. Critchlow, T.D. Sera, R. Mecklenburg, G.<br />

Lindstrom, <strong>and</strong> P. Cartwright. The Design <strong>and</strong> Implementation of a Database<br />

For Human Genome Research. in Eighth International Conference on Scientific<br />

<strong>and</strong> Statistical Database Management. 1996. Stockholm, Sweden: IEEE<br />

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Computer Society Press.<br />

Kerlavage, A.R., M. Adams, J.C. Kelley, M. Dubnick, J. Powell, P. Shanmugam,<br />

J.C. Venter, <strong>and</strong> C. Fields. Analysis <strong>and</strong> Management of Data from High<br />

Throughput Sequence Tag Projects. in 26th Annual Hawaii International<br />

Conference on System Sciences. 1993: IEEE Computer Society Press.<br />

Clark, S.P., G.A. Evans, <strong>and</strong> H.R. Garner, Informatics <strong>and</strong> Automation Used in<br />

Physical Mapping of the Genome, in Biocomputing: Informatics <strong>and</strong> Genome<br />

Projects, D. Smith, Editor. 1994, Academic Press: New York. p. 13-49.<br />

Rozen, S., L.D. Stein, <strong>and</strong> N. Goodman, LabBase: A Database to Manage<br />

Laboratory Data in a Large-Scale Genome-Mapping Project. IEEE<br />

Transactions on Engineering in Medicine <strong>and</strong> Biology, 1995. 14: p. 702-709.<br />

Stein, L.D., S. Rozen, <strong>and</strong> N. Goodman. Managing Laboratory Workflow With<br />

LabBase. in 1994 Conference on Computers in Medicine (CompMed94). 1994.<br />

Stein, L., A. Marquis, E. Dredge, M.P. Reeve, M. Daly, S. Rozen, <strong>and</strong> N.<br />

Goodman. Splicing UNIX into a Genome Mapping Laboratory. in USENIX<br />

Summer 1994Technical Conference. 1994: USENIX.<br />

Goodman, N., S. Rozen, <strong>and</strong> L.D. Stein. Building a Laboratory Information<br />

System Around a C+ +-based Object-Oriented DBMS. in 20th International<br />

Conference on Very Large Data Bases. 1994. Santiago de Chile, Chile: The<br />

Very Large Data Bases (VLDB) Endowment Inc.<br />

8. Mohan, C., G. Alonso, R. Guenthoer, M. Kamath, <strong>and</strong> B. Reinwald. An<br />

Overview ofthe Exotica Research Project on Workflow Management <strong>Systems</strong>. in<br />

6th International Workshop on High Performance Transaction <strong>Systems</strong>. 1995.<br />

9.<br />

Asilomar, CA.<br />

Mohan, C., Tutorial: State ofthe Art in Workflow Management System Research<br />

<strong>and</strong> Products, http://www.almaden.ibm.com/cs/exotica/sigmod96.eps. 1996,<br />

IBM Almaden Research Center.<br />

10. Hollingsworth, D., The Workflow Reference Model,<br />

http://www.aiai.ed.ac.uk:80/project/wfmc/. 1994, Workflow Management<br />

Coalition.

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