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Databases and Systems

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GenBank database query software of, 28–31<br />

homology information of, 21–22<br />

sequence identifiers in, 15<br />

Gene catalogs, in KEGG, 70<br />

Gene Expression Database (GXD), 124–1 26<br />

Genera software, 177, 182<br />

Genes. See also specific types, e.g., BMP<br />

gene<br />

in biochemical pathways, 63–76 ( See also<br />

Kyoto Encyclopedia of Genes <strong>and</strong><br />

Genomes (KEGG))<br />

symbols for, in HGMD, 101–102<br />

299<br />

<strong>and</strong> databases, other, 32<br />

growth rate of, 28f<br />

limitations of, 32–33<br />

perspectives of, 33<br />

scope <strong>and</strong> content of, 24<br />

sequence selection of, 25–26<br />

sequence type definitions of, 22–24<br />

similarity search of, 25–26<br />

HTML, in Biology Workbench, 235–236<br />

Human bone protein-2B (BMP2B), 23<br />

Human Gene Mutation Database (HGMD),<br />

Genetics, OMIM in, 78 99–103<br />

Genome, annotation of, 259–260<br />

data access in, 102<br />

Genome Database (GDB), 85–97<br />

data coverage <strong>and</strong> structure in, 101<br />

dispersion measurement in, 9 1–93<br />

outlookfor, 103<br />

linear alignment in, 87–90<br />

utility of, 99–100<br />

map display in, 94–95, 96f<br />

web address of, 99<br />

map integration in, 93–94<br />

Hyperlinks. See also Links, database<br />

map query in, 86–87<br />

in FlyBase, 148<br />

nonlinear alignment in, 90, 91f<br />

in SRS, 220<br />

OPM tools for, 196<br />

Hypertext navigation, 58<br />

Genome maps, in KEGG, 70<br />

Hypertext objects, in Agricultural Genome<br />

Genome project, NCBI scale-up efforts for,<br />

18<br />

GenomeNet, 64t, 68t<br />

Information System (AGIS), 173<br />

Genomic-map displays, in EcoCyc, 56–57<br />

Gi’s Vs accessions, 15–16<br />

I<br />

GKB Editor, 50 Icarus, 214–215<br />

Grammars, 2 15 Identifiers<br />

Graphical interface, of HOVERGEN, 28–31 in LabBase, 283<br />

Graphical user interface<br />

in metabolic reconstruction system, 38<br />

of bioWidgets, 255–256<br />

of National Center for Biotechnology In-<br />

of EcoCyc, 48<br />

formation (NCBI), 13<br />

Grasper-CL, 58f, 59<br />

of sequence, 14–16<br />

Implementation issues, in object-protocol<br />

model, 198<br />

H Indexing, in SRS, 214–216<br />

Integrated data, for molecular biology re-<br />

H. influenzae, in EcoCyc data base, 48<br />

search, 11–18<br />

H. pylori, in EcoCyc data base, 48<br />

Integrating database (ID), of NCBI, 16–18<br />

Heterogeneous textual databanks, 192, Interfaces<br />

21 3–230. See also Sequence Retrieval of Biology Workbench, 234<br />

System (SRS) of bioWidgets, 255–256<br />

Hierarchical associations, 112–1 13<br />

Common Lisp Interface Manager (CLIM)<br />

Homologous sequences, of vertebrate genes, as, 58<br />

21–33 CORBA as, 246–247<br />

Homology, definition of, 22–24<br />

of EcoCyc, 48<br />

HOVERGEN, 21–33 of HOVERGEN, 28–31<br />

application examples of, 32<br />

IDL as, 247–249<br />

availability of, 33<br />

Java as, 258<br />

classification of, 26–28<br />

of KEGG, 66–67<br />

data treatment of, 24–25<br />

of LabBase, 284

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