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Guidelines for Metals and Metalloids in Ambient ... - ARCHIVE: Defra

Guidelines for Metals and Metalloids in Ambient ... - ARCHIVE: Defra

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Contents<br />

Contents<br />

Terms of Reference<br />

Membership of the Panel<br />

Chairman<br />

Members<br />

Observers<br />

Assessors<br />

Secretariat<br />

Acknowledgments<br />

Summary of recommendations<br />

iii<br />

vii<br />

viii<br />

viii<br />

viii<br />

ix<br />

ix<br />

x<br />

xii<br />

xiii<br />

1 Introduction 1<br />

1.1 Background to the report 1<br />

1.2 General issues 2<br />

1.2.1 Approaches to sett<strong>in</strong>g st<strong>and</strong>ards 2<br />

1.2.2 Additional uncerta<strong>in</strong>ties 4<br />

1.2.3 Exposure to multiple pollutants 4<br />

1.2.4 Susceptible <strong>and</strong> vulnerable groups 6<br />

1.2.5 Units of concentration <strong>and</strong> choice of averag<strong>in</strong>g times 7<br />

1.2.6 Development of the report 9<br />

1.3 How the Environment Agencies will use the guidel<strong>in</strong>e values 9<br />

1.4 Introduction to the metals <strong>and</strong> metalloids 11<br />

1.4.1 Physio chemical characteristics 11<br />

1.4.2 Key human health effects <strong>and</strong> their <strong>in</strong>fluence on<br />

safety factors 12<br />

1.4.2.1 Lung cancer 12<br />

1.4.2.2 Irritation/<strong>in</strong>flammation 13<br />

1.4.2.3 Hypersensitivity 14<br />

References 15<br />

iii

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