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il\VOLVEMENT OF RETII\OIC ACID II{ - MSpace at the University of ...

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IV.b.3. The uptake to peripheral tissues<br />

IV.b.4. Integr<strong>at</strong>ive role <strong>of</strong> retinoid binding<br />

proteins in retinoic acid metabolism<br />

IV.b. 5.Retinoic acid c<strong>at</strong>abolism<br />

IV.c. Retinoic acid and cell signaling<br />

fV.c.l.Introduction<br />

lV.d. Retinoic acid functions<br />

IV.c.2.The structure <strong>of</strong> retinoic acid receptors<br />

<strong>II</strong>Lc.3.Retinoic acid receptors distribution<br />

<strong>II</strong>I.c.4. Signaling p<strong>at</strong>hway<br />

IV.d.l.The role <strong>of</strong> retinoic acid in oardiovascular<br />

system<br />

IV.d.2.Pren<strong>at</strong>al life<br />

fV.e. Retinoic acid and apoptosis<br />

lV.d.3.Postn<strong>at</strong>al development<br />

IV.e. 1. Receptor-dependent p<strong>at</strong>hway<br />

N .e.2. Receptor-independent p<strong>at</strong>hw ay<br />

IV.f. Retinoic acid and oxid<strong>at</strong>ive stress<br />

39<br />

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v. RAR's and peroxisome prolifer<strong>at</strong>or-activ<strong>at</strong>ed receptors (ppAR's) in<br />

oxid<strong>at</strong>ive stress and apoptosis<br />

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V.a. Distribution and function <strong>of</strong> PPAR receptors<br />

V.b. Mechanism <strong>of</strong> transcriptional regul<strong>at</strong>ion<br />

V.c. PPAR and Apoptosis<br />

V.d. PPAR and oxid<strong>at</strong>ive stress<br />

V.e. The role <strong>of</strong> PPAR receptors in <strong>the</strong> cardiovascular system<br />

V.f. PPAR and heart Failure<br />

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HYPOTHESIS<br />

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1r1

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