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96 RADIUM NEW BOOKS Albert Bachem. Ph. D. Principles of X-ray and Radium Dosage. Published and sold by the author. 502 Oakwood Boulevard. Chicago. Illinois, 1923. S8 postpaid. In this volume of 274 pages, containing 70 illustrations and 38 charts, the author seeks to give the clinical worker with x-rays and radium (1) an exact definition and the methods of measurement of ray intensity and hardness; (2) a discussion of the distribution of x-ray and radium rays in tissues in' the light of recent physical investigations; (3) a discussion of relative and absolute dosage; (4) data as to the dosage employed in practice, illustrated by a series of casse as treated in the light of the most recent developments of deep roentgen therapy. The important work of Kroenig and Friedrich on the Principles of Physics and Biology of Radiation Therapy was written from the laboratory rather than the clinical standpoint, and for this reason was somewhat abstract and more difficult to make use of by the busy clinical worker, who could not devote the necessary time for 'research to apply the principles laid down in Kroenig and Friedrich's epoch-making book. Dr. Bachem seeks to bridge this gap between the abstract principles of ray measurement and dosage and their clinical application, ami to the extent that present understanding of dosage and clinical results permit he has succeeded admirably. Considerably more space in the book is devoted to the discussion of the x-ray work tham is given to radium. This is only a natural outcome of the greater difficulties which the x-ray dosage presents as compared with dosage of the radium rays. In the case of the x-ray, both the penetrating power (wave length) and the intensity of the rays may varv. whereas in the case of radium, the quality of the rays is constant, and ray intensity is the important factor in determining dosage and clinical effect. As far as it may be set down with the present knowledge of skin erythema dose (and it may be remarked parenthetically that these data are largely due to the workers in the physical department at the Memorial Hospital. Xew York). Dr. Bachem has tabulated the erythema skin dose in milligram hours for various screenings and distributions of the radium, placed at different distances from the skin surface. In the bringing together of such data, this book has rendered a valuable service, and merils a careful reading and study by the radium and roentgen therapist. Radium Report of the Memorial Hospital. Xew York, (second series. 1923) Paul B. Hoeber. Inc., Xew York, 1924. xii. 293 pp. with 55 illustrations. $5. This most important and eagerly awaited report has just appeared. Due to the fact that the April issue of Radium is in press, a review of the book will appear in the July issue.
A QUARTERLY JOURNAL DEVOTED TO THE CHEMISTRY. PHYSICS AND THERAPEUTICS OF RADIUM AND RADIOACTIVE SUBSTANCES Copyright 1924 by Radium Chemical Co. Edited by Charles H. Viol. Ph. D., and William H. Cameron. M. D.. with the assist collaborators working in the fieldsof Radiochemistry. Radioactivity and Radiumtherapy. Address all communications to the Editors. Forbes and Meyran Avenues, Pittsburgh. Pa. Annual Subscription $2.00. Single Copies 50 Cents. VOL. 3, New Series JULY, 1924 No 2 CARCINOMA OF THE BODY OF THE UTERUS (WITH THE REPORT OF 115 CASES)* By Charles C. Norris, M. D*. and M. E. Voct, M. D. Philadelphia. Pa. With the advent of radium, the study of carcinoma has received a great stimulus, and perhaps in no variety greater than that which occurs in the uterus. Probably owing to the unsatisfactory results secured by operative intervention and probably also to the greater frequency of the neoplasm, this interest has been rather centered about cervical cancer. The following study embodies the results obtained by operation and irradiation in a series of 115 consecutive carcinomata of the body of the 'uterus, especially emphasizing the end-results. Carcinoma of the uterus may be divided into that form which originates in the cervix and that which springs from the fundus. These are different tumors, histologically and clinically, and a definite line should he drawn between them. Carcinoma of the fundus is less common than that of the cervix. Among 12.514 gynecologic patients observed during the last 23 years at the University Hospital, there have been 115 cases of fundal carcinoma. During a like period 346 cases of cervical carcinoma have been observed among 756 cases of carcinoma of the genital tract. Thus in our series, carcinoma of the fundus constituted about 15.2 per cent of all cancers of the genital tract and about 25 per cent of all uterine cancers. Frank1 places the former figure between 10 to 15 per cent; Peterson2 18.8 per cent; and Wilson3 11.2 per cent. It is an established fact that chronic irritation is a distinct predisposing factor towards cancer. Cervicitis, especially in cervices which "Reprinted by permission from The American Journal or Obstetrics and Gynecology, vll. 55
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PRESENTED BY PUBLISHER
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CONTENTS OF VOLUME THREE. NEW SERIE
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F. W. Aston, D.Sc, F.R.S. Atoms and
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2 Radium P. M. the apparatus is app
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Radium value of the metal container
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Radium Table I—Continued Classifi
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8 RADIUM The affections of the thyr
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10 R a d i u m The treatment should
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12 Rapitjm ooo per cubic millimetre
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14 Radium tines of tubercle bacilli
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16 R A D I U M 4. Lymphatic Leukaem
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18 RADIUM than in anv other organs
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20 R a d i u m In a previous paper
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99 Radium 2 mm. thick; the whole ap
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2-1 Radium inum tubes in use. These
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26 R a d i u m 5-gr. capsule and sw
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28 R A D I U M 1 tared, as in the f
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80 R a d i u m (6) The greatly less
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32 R a d i u m and at times three,
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04 R a d i u m capsule is placed un
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36 R a d i u m 1 have observed one
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38 R A D I U M Frequency and Distri
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10 R a d i u m holder with comparat
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42 HADITJ M gestion of the eve whic
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44 R a d i u m The low polymorphonu
Page 54 and 55: 46 Radium examined, it is believed
Page 56 and 57: 48 I^ADITJM Positive results of exp
Page 58 and 59: 50 R a d i u m 1 Is e III , -m If "
Page 60 and 61: »2 R a d i u m The summary of phys
Page 63 and 64: Radium 55
Page 65 and 66: R a d i u m 57 s V. — •7 CO N
Page 67 and 68: R a d i u m 59 Measuring radium by
Page 69 and 70: R a d i u m 6i Bibliography I. Gudz
Page 71 and 72: R a d i u m 68 Ited cells, SUBJECT
Page 73 and 74: R a d i u m TECHNIQUE OF RADIUM TRE
Page 75 and 76: R a d i u m B7 INDEX OF ARTICLES RE
Page 77 and 78: R a d i u m 69 Bower, J. O. and Cla
Page 79 and 80: R a d i u m 71 —Treatment of mali
Page 81 and 82: R a d i u m 73 —Carcinoma of oeso
Page 83 and 84: R a d i u m 75 —Uses of radium in
Page 85 and 86: R a d i u m 77 Kimbrough. J. B. and
Page 87 and 88: R a d i u m 7^ Lymph Nodes—Histol
Page 89 and 90: R a d i u m si Nicolich—Carcinoma
Page 91 and 92: R a d i u m 83 Radium— —Large d
Page 93 and 94: a d i u m 85 -Physical conditions o
Page 95 and 96: R a d i u m ST Arch. f. Gynak. 118:
Page 97 and 98: R a d i u m 89 Scholten, G. C. J.
Page 99 and 100: R a d i u m 91 (A. J. Larkin) Am. J
Page 101 and 102: R a d i u m 93 —Xecessity for com
Page 103: RADIUM 95 Wallerstein, E. U.—X-ra
Page 107 and 108: R a d i u m 99 casionally a carcino
Page 109 and 110: R a d i u m 101 would be detected w
Page 111 and 112: R a d i u m 103 cially likely if th
Page 113 and 114: R A D I U M 105 radium irradiations
Page 115 and 116: R a d i u m 107 that in nearly ever
Page 117 and 118: R a d i u m 109 liver and lung meta
Page 119 and 120: Radium in Appleton Co., 1922. (2) P
Page 121 and 122: R a d i u m 113 BLOCKING LYMPHATICS
Page 123 and 124: R a d i u m 115 removed, and the ra
Page 125 and 126: R a d i u m in PATHOLOGY Pathologic
Page 127 and 128: 4. Cauhape: Thesis. Paris. 1911. R
Page 129 and 130: R a d i u m 121 is necessary by thi
Page 131 and 132: Radium 123 is injected into the tis
Page 133 and 134: R a d i u m 125 (3) Polonaise Numbe
Page 135 and 136: R a d i u m 127 modern laboratories
Page 137 and 138: R a d i u m 129 NINTH ANNUAL MEETIN
Page 139 and 140: R a d i u m 131 Several distinguish
Page 141 and 142: R a d i u m 133 which X-rays or rad
Page 143 and 144: R A D I U M 135 In the autobiograph
Page 145 and 146: R A D I U M 137 of radical operatio
Page 147 and 148: R a d i u m 139 reports 26 cases, 8
Page 149 and 150: R a d i u m 141 George W. Crile, M.
Page 151 and 152: R a d i u m 143 "In carcinoma of th
Page 153 and 154: R a d i u m 145 " 1 he principal ob
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IUM 147 have found no means of obvi
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R a d i u m 149 and six hours. Now
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R a d i u m 151 thoroughly transfix
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R a d i u m 153 weakness, palpitati
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R a d i u m 155 had all been benefi
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R a d i u m i57 tation of the kidne
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Radium 159 Can walk only with a can
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A QUARTERLY JOURNAL DEVOTED TO THE
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R a d i u m 163 in operative clinic
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a d i u m 165 In Table II we have d
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Hajmu.m 167 tery was used in combin
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R a d i u m 169 TABLE IX.—RESULTS
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R a d i u m m Radium alone Class i.
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R a d i u m 173 and papillary carci
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R a d i u m 175 It grows rapidly, i
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R a d i u m 177 emanation tubes. Th
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R a d i u m 179 never at any time f
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R a d i u m 181 THE TREATMENT OF MA
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R a d i u m 183 Cast 3. Carcinoma a
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R a d i u m 185 Chm 7. Showing cond
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R a d i u m 187 courting disaster b
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R a d i u m 189 radium in the treat
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R a d i u m 191 Histologic changes
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R a d i u m 193 about their involut
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R a d i u m 195 due to x-ray, sunli
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R a d i u m 197 zation of a partial
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R a d i u m 199 to report his cases
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201 very often will result in a dec
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R a d i u m 203 the cautious use of
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IUM 205 On Jan. 14th. which was a v
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CONCLUSIONS 207 That in some cases
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R a d i u m 209 (b) The fluorescent
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R a d i u m •, 211 patient. The p
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R a d i u m 213 radiological depart
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R a d i u m 215 fortunately, the im
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R a d i u m 217 know whether such c
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R a d i u m 219 eight months had el
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R a d i u m 221 "The selective and
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R a d i u m 223 of a simple unitary
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A QUARTERLY JOURNAL DEVOTED TO THE
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R a d i u m 227 in their beta ray a
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R a d i u m 229 or the gradation of
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R a d i u m 231 be left in malignan
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R a d i u m 233 during repeated cau
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R a d i u m 235 3. The presence of
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R a d i u m 237 situated at the lim
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R a d i u m 239 REFERENCES 1. Wickh
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Rajpium 241 the test of five years,
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R a d i u m 243 comparative statist
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R a d i u m 245 end results of 201
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R a d i u m 247 Operation Hysterect
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R a d i u m 'IV.) and five years, a
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R a d i u m 251 or effect upon, the
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R a d i u m 253 2. Early Cases.—T
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R a d i u m 255 groups: the superfi
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R a d i u m 257 "I am becoming more
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R a d i u m 259 ment of 'Radiumhemm
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R a d i u m 261 unusual symptoms an
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R a d i u m 263 dition continued sa
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R a d i u m 265 died from hemorrhag
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R a d i u m 267 equals 132 millicur
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R a d i u m 269 "The data in the li
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R a d i u m 271 animals a diminutio
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R a d i u m 273 rays as contrasted
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R a d i u m 275 depression than a d
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R a d i u m 277 repeated operations
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R a d i u m 279 tonsil completely,
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Radium 281 Ihe tonsil is dangerous
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R a d i u m 283 WILLIAM H. B. AIKIN
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DEVOTED TO THE CHEMISTRY, PHYSICS A
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PUBLISHED SEMI-ANNUALLY AND DEVOTED
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R a d i u m 3 ORAL CANCER The next
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lymph nodes in even case, but when
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adiation up to 2400 milligram hours
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R a d i u m o radium to relieve pat
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R a d i u m 11 Uterine Fibroids The
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R a d i u m i3 by some operators. X
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R a d i u m 15 from the operation h
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R a d i u m n tions, the distance s
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R a d i u m 19 APPENDIX RADIUM AND
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Radium 21 BASIC AND CONTBIBUTING FA
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RA.PIUM 23 X-RAY AND RADIUM THERAPY
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R a d i u m 25 Since, by the impact
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R a d i u m 27 duccd which were cov
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R a d i u m 29 In other cases the g
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R a d i u m 31 The recital of this
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R a d i u m 33 index of articles re
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R a d i u m 35 Block, F. B., and Cl
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R a d i u m ?,- J. R. Ranson) Color
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R a d i u m :;:» —Epithelioma of
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R a d i u m 4I Forsdike. S.-Cancer
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R a d i u m 43 Hot Springs, Arkansa
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R a d i u m 45 Lee. B. J., and Here
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R a d i u m 47 Mineral Waters, exam
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R a d i u m 49 —Treatment of inop
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R a d i u m 51 - Metabolic changes
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R a d i u m 58 Radium, emanation—
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R a d i u m .>.) —Physiological a
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R a d i u m 57 —Experimental rese
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R a d i u m 59 Spleen, physiology
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R a d i u m 6l —Animal tumor cell
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R a d i u m es —Treatment of uter
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PUBLISHED SEMI-ANNUALLY AND DEVOTED
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R a d i u m e? CONTRAINDICATIONS TO
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R a d i u m 69 in addition to the i
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Radium 71 the most common, in the o
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R a d i u m ?:; nexae is a positive
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R a d i u m 76 essential to success
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R a d i u m 77 Our technique is to
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carcinoma of the CERVIX R a d i u m
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R a d i u m 81 a bleeding, cauliflo
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R a d i u m HS Fibrinous patch on e
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R a d i u m sr, mal 7 days later. A
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R a d i u m ST idly develops and me
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R a d i u m 89 2. Cervical cancer o
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R a d i u m 91 irradiation treatmen
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R a d i u m 93 by a study of curett
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R a d i u m 96 parenchyma eventuall
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R a d i u m 97 ihe lowest (2) was t
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R a d i u m 99 3. The treatment int
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R a d i u m 101 harder and shows on
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a d i u m 103 Sloughy Not sloughy .
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R a d i u m 105 But 2 of 15 cases h
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R a d i u m 107 Sice (not of tumor,
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IUM 109 Time well Number of cases i
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R a d i u m 111 died of a secondary
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R a d i u m 113 epithelioma of the
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R a d i u m 115 This writer also fo
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R a d i u m 117 as held by many wri
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R a d i u m 119 of foods, particula
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R a d i u m 121 which, in the last
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R a d i u m 123 "It has long been r
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R a d i u m 125 OBITUARY JAMES C. G
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