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R a d i u m 111<br />

died of a secondary growth in the urethra, with metastases to the inguinal<br />

glands.<br />

Radium dose, infiltrating carcinoma<br />

Cases well -g<br />

Bare tubes alone g*<br />

Screened radium alone<br />

4V<br />

Bare tubes and screened radium 4<br />

Unscreened radium held against tumor and screened<br />

radium<br />

ij<br />

Bare tubes and unscreened radium 1<br />

*One case multiple treatment through cystoscope.<br />

IGne case 2 treatments: one case 3 treatments.<br />

(Three treatments.<br />

There were 8 cases in which bare tubes alone were used. In these<br />

8 cases the strength of the bare tubes varied between 0.2 and 3.0 millicuries.<br />

and 1 to 2 tubes to each cubic centimeter were used. In 5 of<br />

the 8 cases bare tube treatment alone succeeded in removing the carcinoma.<br />

In 3 cases, subsequent treatments were necessary to destroy<br />

the growth.<br />

SQUAMOUS CARCINOMA<br />

In 61 cases of infiltrating carcinoma there were 3 cases of squamous<br />

carcinoma. As far as I could *ce there was no way in which the<br />

diagnosis could be made prior to sectioning. They resembled any other<br />

flat infiltrating carcinoma. I believe they are more malignant than most<br />

carcinomas, and are somewhat more resistant to radium treatment. Of<br />

these 3 cases. 1 is well, and 2 are dead or dying.<br />

REASONS FOR FAILURE OF RADIUM IN* SOME CASKS<br />

In 2 cases we tried to implant radium in the base of the tumor without<br />

firstsnaring the tumor off. Boih of ihese cases were pretty extensive,<br />

and one especially very malignant. I am convinced we would have<br />

done better in these cases had we snared the tops of the tumors off,<br />

because wc should have been able to more accurately implant the base<br />

with radium, and the good results we have had are due to this very accurate<br />

implantation. All cases that have had a definite submucous extension<br />

is covered with normal mucous membrane. It is, as a rule, difficult<br />

to see. but can easily be felt. Notwithstanding we have had several<br />

cases in which the tumors have been removed by implanting bare tubes<br />

of the strength of 0.2 millicuries. such cases are rare, and the strength<br />

most useful is 0.6 to 0.7. There have been several cases in which it has<br />

seemed that we ought to have removed the tumor, and the reason that<br />

we have not done so was that we did not reinforce the bare tubes by<br />

the addition of screened radium to the surface of the tumor base.<br />

PRESENT ESTIMATE OK PROPER RADIATION<br />

Dr. Adair has suggested that various parts of the body be dividec'<br />

into sensitive and insensitive areas, and the method of radiation be<br />

varied according to the relative sensitiveness of the parts treated. This<br />

condition applies very well to the bladder, all parts of which are fairly

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