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242 RADIUM<br />

Carcinoma of the Accessory Sinuses will sometimes yield to radiation.<br />

Recently a young man of twenty-one years was referred to me<br />

by Dr. John B. Deaver. Dr. Ralph Butler and Dr. K. Bauer, with carcinoma<br />

involving especially the ethmoid region. A section examined<br />

by Dr. Stanley Reimann showed prickle-cell carcinoma, with a chain<br />

of metastatic lvmph nodes extending down the left side of the neck. So<br />

far as any of'us can tell, all evidence of the disease has disappeared<br />

under thorough cross-fire with the high voltage x-ray*. This will serve<br />

as an example of what will likely be the method of choice in the future<br />

in treating carcinoma and sarcoma of the accessory sinuses.<br />

Carcinoma of the Larynx will sometimes yield to radiation. I have<br />

found the introduction of radium into the tumor, through the thyrohyoid<br />

membrane, to be helpful.* It is advisable to do a tracheotomy in advance<br />

so as to prevent complications. Then a preliminary course of<br />

x-rays covering even- part of the disease should be given. Radium<br />

needles can afterward be inserted through the thyrohyoid membrane<br />

into the diseased area, and ten milligram needles can be left in place<br />

about six hours. Wc have been at least favorably impressed with this<br />

line of action.<br />

Carcinoma of the Esophagus.—Heretofore, these cases have been<br />

looked upon as hopeless. The brilliant work done by Drs. Mills and<br />

Kimbrough' gives us some encouragement in their radiation treatment.<br />

Their general result* are:<br />

Cured o<br />

Total 45<br />

Palliative result good 12<br />

Palliative result fairly good 12<br />

Palliative result fair 14<br />

Palliative result poor 4<br />

Palliative result negative 3<br />

Xo cures are recorded, but one patient lived three and a half years.<br />

dying finallyof tuberculosis and exhaustion. This was one of the cases<br />

rated as "palliative good." It is significant that only three cases failed<br />

to obtain some palliative result. Dr. Mills referred to one case that.<br />

three months previously, was thought to have about three weeks to live.<br />

and who. at the time of the report, was walking twelve miles a day as<br />

an inspector. Some additional help may also be obtained by treating<br />

with high voltage x-rays.<br />

Carcinoma of the Breast.—The treatment of primary carcinoma of<br />

the breast with radiation is not new, and the primary cases referred for<br />

treatment have been nearly always very far advanced; but when one of<br />

these advanced cases is cured we feel that a great deal has been accomplished.<br />

Possibly we may some day be able to consider fairly the relative<br />

value of surgical extirpation and treatment by radiation primarily.<br />

but this will be possible only when the surgeon and radiologist can see<br />

patients together, preliminary to treatment. The diagnosis should then<br />

be made by them jointly; or better, a diagnosis made without reference<br />

to treatment. The patients should be carefully classified and then a considerable<br />

number of each class treated by each method. The operations<br />

should be performed by a thoroughly competent surgeon and the radiation<br />

should be given by an equally competent radiologist. Such an ideal<br />

arrangement is most difficult to obtain, but until such conditions prevail.

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