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Presentation: A New DOE Paradigm - JMP

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Screening Conundrum – Two Models<br />

The full model containing both 6 first-order and 15 secondorder<br />

terms is:<br />

But n = 12, so we can only fit the intercept and the main<br />

effects:<br />

Standard result: some main effects estimates are biased:<br />

where the “alias” matrix is:<br />

71

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