t - New York Civil Liberties Union

084
Union-Endicott
! -::----.-----. ABoûfTHE ftESEARCH -_ .....
-. He~ are S~~le an~~ ~rsabout cui'rent . --~'ral sUb~ce; ~id;i~~~~~t
, AIDS research provldec byaJeadlngAIDS ; In the body, ltil role Is to signal iníec
. researcher, Anthony Fa lcl, director of the fighting white blood calls, known as
National Institute of AilErgy.and Infectious cells. to begin dividing. .
Disease, and other sou ces. Q. Whit role do Ihøs. white
Question: Have d~leton cured blood cells play In HIV Inf&ctlof,
AIDS?
A. To answer that. It is Important,
.. ._.... .__ Answer: No, They i lave found that a know how CD4 cells work In people 'i
potent dose of an Imm me system stlmu- are not Infected with HIV,
lant ~an kill virtually all of the AIDS vlrus, In hèalthy people, CD4 cells are gil'
I HIV, In the body, .. . als In the body's onslaught against di} I
Q._~yJSIl1!UhaLi.cur8? '.. '".''' ease.They·eommand·the·other-lmml;j~· ~;-
A. With HIV, you hal e to kill all of the'~ cells In the body to attack bacteria am .
virus no matter where t lurks, in blood Or',H viruses.
tissue, Even Ilt few SUri Ivlng viruses can HIV'lnvades these cells, When they
l sow the seeds of IIfe-tllreatenlng Infee- , activated by Infection Dr some other
It':;too soon to can from the disappointment last year tlon IhroughouUhe itrll nune syster)1all means CD4 T-cells become virus fac;
of finding chat certain inactive over again, . r: ries P¡oduclng large Quantities of vlru
it fil cure, experts say immunecell:-;iJ:1AIDSpatjentsh~l'. Q.Hasa~yoneeV&rbeenClOnsld. Q.lsthaulltbeydO?
bor lat~nt VJ.l'US for years, despite ered curedW . ,. . A. No, Some of them, known as rEIS
GII\I~NETt NhWS SERVICE ot!wrwlse su~:es~ful treatment. A. No: In one ~ase, a rnan ~own to.. . Ing CD4 T-cells, become safe havens
A bëJ;fåpproachto AIDS treat- ro get a~,\ his VIruS, doctors gave the PLIblieonly ~sthe IlerlIn.patl~nt,a .' -: . latent virus, sheltering It from anti-HIV
mer t appears for the first time to . 14 patients. taking standard drugs course of HIV:kHlIng dl ugs er!ldlpated;-'drilgs, ...," ,'.. .
. hav, ~flushed virtually all HIV from additional courses of the iinmunel most of the VIrUS and l1enhlsJmmu~~, ..:. Q. How' dols 'Hnf hide from the.
the olood of three patients, a "top stimulant interleukin 2. or IL·2, tal system took over, keelllng,._~I~.lpfectiO~at':.èlruP'l,:';:',.,,::: j ...?: . .,
researcher said Sunday,. . activate quiescent c,ells and force bay. . h' ·"b'·'k···· .,. A.-HIV, like aWvlruses. is essentiall\
A. biopsy of one patient's lymph . them to chum out VIruS. The virus as not c( me ae even. bundle of genes, When HIV Infects a
. nod! ~- where lívevlrus is com. Flushingout the virus exposes if' ~hOUg'1!ey~~ ~~gP ¡dtaking a,ntl-HIV . white blood cell, those genes literally
mady abundant in HIV -infectéd to the pO,tent ant¡ ..HIV drugs, .[n rugs ',. stitch themselVes into the genes of thi
pat; ~nlts -·-also proved negative ~heo:y, thiswould clearthe,remalll' I %1~::I:ü:':
:::P:ú::r:nd . Infected cell so they can't be unrayele
usi!'1 g the most seusitive tests avail- mg vlru~ fr,om tbe body, as It appar- h~~ did H 'Nerk? • When the body's Irrymune system ISal
abh, said Antbony Faúcî, of the ently did m three patients, In all A T nty~six men Nere enrolled vated to fight infection, HIV ISactivate,
Nat onal Institute. of Allergy and three, doctors failed to grow live • we , ' too, Rather than dividing, as it should
1nf(: eti,o.I,.\S Diseases, Betl.lesda.· ,Md.. HIV from 3