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Global Tuberculosis Control 2010 - Florida Department of Health

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ogress made towards achieving the impact targets<br />

set for 2015 – to halt and reverse the incidence <strong>of</strong> TB<br />

by 2015 (MDG Target 6.c), and to halve prevalence and<br />

mortality rates compared with a baseline <strong>of</strong> 1990 (the<br />

targets set by the Stop TB Partnership) – is illustrated<br />

at the global level in and at the regional level<br />

in , and . 1 Progress in<br />

achieving reductions in incidence and mortality is shown<br />

for each <strong>of</strong> the 22 HBCs in and .<br />

<strong>Global</strong>ly, rates <strong>of</strong> incidence, prevalence and mortality<br />

are all declining (). Incidence rates are falling<br />

slowly, at around 1% per year, following a peak at just<br />

over 140 cases per 100 000 population in 2004. If current<br />

trends are sustained, then MDG Target 6.c will be<br />

achieved. Mortality rates have fallen by one third since<br />

1990, and prevalence rates are also in decline. Projections<br />

suggest that the target <strong>of</strong> halving mortality by<br />

2015 compared with 1990 could be achieved at global<br />

level. The target <strong>of</strong> halving the prevalence rate appears<br />

out <strong>of</strong> reach. It should be noted, however, that there is<br />

more uncertainty about trends in prevalence, compared<br />

with trends in mortality (see also ).<br />

Regionally, incidence rates are declining in five <strong>of</strong><br />

WHO’s six regions (). The exception is the<br />

South-East Asia Region (where the incidence rate is stable),<br />

largely explained by apparent stability in the TB<br />

incidence rate in India. Further evaluation <strong>of</strong> trends<br />

in the disease burden in India is needed, and has been<br />

planned for early 2011. Among the five regions where<br />

incidence rates are falling, the rate <strong>of</strong> decline varies from<br />

less than 1% per year in the Eastern Mediterranean and<br />

European regions to around 2% per year in the African<br />

Region (since 2004) and 4% per year in the Region <strong>of</strong><br />

the Americas. As also illustrated in , notifications<br />

are closest to estimated incidence in the Region <strong>of</strong><br />

the Americas and the European Region, indicating that<br />

the highest rates <strong>of</strong> case detection are achieved in these<br />

regions (see also ). As incidence falls slowly,<br />

notifications are increasing in the African Region and<br />

(particularly since 2000) in the Eastern Mediterranean<br />

and South-East Asia regions, indicating improving rates<br />

<strong>of</strong> case detection. In the Western Pacific Region, notifications<br />

increased sharply between 2002 and 2006, but<br />

have since stabilized; here, patterns are strongly influenced<br />

by China, which accounts for almost 70% <strong>of</strong> incident<br />

cases in this region ().<br />

The latest assessment for the 22 HBCs suggests that<br />

incidence rates are falling or stable in all countries<br />

except South Africa (). Trends in incidence<br />

rates are assumed to be stable in Afghanistan, Bangladesh,<br />

India, Indonesia, Myanmar and Pakistan, in the<br />

absence <strong>of</strong> convincing evidence to the contrary (<br />

). The stability in TB incidence rates in India (which<br />

accounts for 61% <strong>of</strong> cases in this region) as well as Bangladesh,<br />

Indonesia and Myanmar explains the flat trend<br />

in estimated incidence in the South-East Asia Region.<br />

<br />

<br />

<br />

<br />

<br />

<br />

<br />

Incidence and notifications Mortality Prevalence<br />

140<br />

35<br />

300<br />

Rate per 100 000 population<br />

120<br />

100<br />

80<br />

60<br />

40<br />

20<br />

30<br />

25<br />

20<br />

15<br />

10<br />

5<br />

250<br />

200<br />

150<br />

100<br />

50<br />

0<br />

0<br />

0<br />

1990 1995 2000 2005<br />

1990 1995 2000 2005 <strong>2010</strong> 2015 1990 1995 2000 2005 <strong>2010</strong> 2015<br />

1<br />

See in <strong>of</strong> this report for definitions <strong>of</strong> the global<br />

targets for TB control.

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