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Global Tuberculosis Control 2010 - Florida Department of Health

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Africa The Americas Eastern Mediterranean<br />

60<br />

50<br />

40<br />

10<br />

8<br />

6<br />

40<br />

30<br />

Rate per 100 000 population<br />

30<br />

20<br />

10<br />

0<br />

15<br />

20<br />

4<br />

10<br />

2<br />

0<br />

0<br />

Europe South-East Asia Western Pacific<br />

40<br />

60<br />

10<br />

5<br />

0<br />

1990 1995 2000 2005 <strong>2010</strong> 2015<br />

50<br />

40<br />

30<br />

20<br />

10<br />

0<br />

30<br />

20<br />

10<br />

0<br />

1990 1995 2000 2005 <strong>2010</strong> 2015 1990 1995 2000 2005 <strong>2010</strong> 2015<br />

<br />

<br />

In most <strong>of</strong> the HBCs, notifications have been getting<br />

closer to estimated incidence in recent years, notably in<br />

Afghanistan, Bangladesh, Cambodia, China, Indonesia,<br />

Pakistan, South Africa and the United Republic <strong>of</strong> Tanzania<br />

().<br />

Prevalence rates are falling in all six WHO regions (<br />

). The most impressive progress is in the Region<br />

<strong>of</strong> the Americas, where the Stop TB Partnership’s target<br />

<strong>of</strong> halving the 1990 prevalence rate has been achieved.<br />

Projections suggest that the Western Pacific and Eastern<br />

Mediterranean regions are on track to achieve the target<br />

by 2015, and the European Region could get close. On<br />

current projections, the African and South-East Asian<br />

regions will not achieve the target.<br />

Mortality rates (excluding TB deaths among HIVpositive<br />

people) are falling in all six WHO regions. The<br />

best progress towards the 2015 target <strong>of</strong> halving the<br />

1990 mortality rate is in the Region <strong>of</strong> the Americas and<br />

the Western Pacific Region, both <strong>of</strong> which appear to have<br />

achieved the target already. The Eastern Mediterranean,<br />

European and South-East Asia regions are close to reaching<br />

the target, and could do so before 2015. In the African<br />

Region, achieving the target appears out-<strong>of</strong>-reach,<br />

following a major increase in TB incidence and mortality<br />

rates associated with the HIV epidemic throughout the<br />

1990s and up to around 2004.<br />

Among the 22 HBCs, mortality rates appear to be<br />

falling with the possible exception <strong>of</strong> Afghanistan and<br />

Uganda ( ). Even allowing for uncertainty in<br />

these estimates, four countries reached the target <strong>of</strong><br />

halving the 1990 mortality rate by 2009 (Brazil, Cambodia,<br />

China and the United Republic <strong>of</strong> Tanzania), and<br />

six additional countries (India, Indonesia, Kenya, Myanmar,<br />

Pakistan and the Russian Federation) have a good<br />

chance <strong>of</strong> doing so by 2015. In the other HBCs, current<br />

forecasts suggest that the target may not be achieved.<br />

The reductions in mortality associated with progress<br />

to date in implementing the DOTS strategy (1995–2006)<br />

and its successor, the Stop TB Strategy (launched in<br />

2006) have saved millions <strong>of</strong> lives since 1995, and continued<br />

implementation could save millions more in the<br />

years up to 2015 ( ). 1 From 1995 to 2009, 49<br />

1<br />

These results are based on the following manuscript: Glaziou P et<br />

al. Lives saved by tuberculosis control and prospects for achieving<br />

the 2015 global target for reductions in tuberculosis mortality<br />

(submitted for publication in May <strong>2010</strong>).

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