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February 27, 2012 - IMM@BUCT

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news of the week<br />

FEBRUARY <strong>27</strong>, <strong>2012</strong> EDITED BY WILLIAM G. SCHULZ & SOPHIA L. CAI<br />

DIOXINS,<br />

ASSESSED AT LAST<br />

POLLUTION: After years of study,<br />

EPA sets safe level of exposure<br />

to the most toxic congener<br />

AFTER 21 YEARS of contentious scientific analysis,<br />

the Environmental Protection Agency has<br />

established a safe level of exposure to the most<br />

toxic form of dioxin.<br />

EPA set a safe daily dose of 0.7 picograms of<br />

2,3,7,8-tetrachlorodibenzo- p -dioxin (TCDD) per kilogram<br />

of body weight. TCDD is the most potent congener<br />

of the dioxins, which generally are unintentional<br />

by-products of manufacturing processes involving<br />

chlorine and burning of biomass or waste.<br />

Eventually, this defined level of safe exposure will<br />

affect the degree—and cost—of cleanups of soil and of<br />

industrial air and water releases polluted with dioxins.<br />

This category of chemicals consists of chlorinated<br />

dioxins and furans and certain polychlorinated biphenyls.<br />

These substances can trigger similar adverse<br />

health effects, but their potencies vary.<br />

The exact regulatory impacts of the agency’s determination<br />

, which was released on Feb. 17, are as yet uncertain.<br />

EPA’s new level “will serve as the cornerstone<br />

of the agency’s initiatives to protect public health from<br />

chemical contaminants and provide the necessary<br />

guidance to states and public health agencies to minimize<br />

dioxin exposure,” says Olga Naidenko, a senior<br />

scientist with the Environmental Working Group, an<br />

activist group.<br />

The American Chemistry Council, an industry organization<br />

that has invested much time and energy in<br />

influencing EPA’s work on this assessment, calls the<br />

agency’s conclusions “flawed.”<br />

Lois Marie Gibbs, executive<br />

director of the Center for Health,<br />

Environment & Justice, an environmental<br />

group that has focused<br />

on dioxin issues for years, hails<br />

the long-awaited completion of<br />

the agency’s effort. “The American people,” she says,<br />

“won a major victory against the chemical industry,<br />

which has been working behind closed doors for decades<br />

to hide and distort the truth about the dangers of<br />

dioxin.”<br />

Data in EPA’s annual Toxics Release Inventory indicate<br />

that U.S. industry has slashed its releases of dioxins<br />

in the past two decades (C&EN, Feb. 6, page 26).<br />

Cl<br />

Cl<br />

O<br />

O<br />

2,3,7,8-Tetrachlorodibenzo-p-dioxin<br />

Backyard waste burning is the major source of dioxins<br />

in the U.S. today.<br />

The EPA limit is based on two studies. One found<br />

adverse reproductive effects in men exposed to TCDD<br />

as boys. The other found hormonal effects in infants<br />

born to mothers who had high levels of exposure.<br />

People are exposed to dioxins mainly by eating<br />

meat, poultry, dairy products, fish, or eggs. However,<br />

EPA claims that “most Americans have only low-level<br />

exposure to dioxins,” adding that this “does not pose a<br />

significant health risk.”<br />

The agency’s document examines health effects<br />

other than cancer from TCDD exposure. They include<br />

chloracne, a severe skin disease producing acne-like<br />

WWW.CEN-ONLINE.ORG 5 FEBRUARY <strong>27</strong>, <strong>2012</strong><br />

Cl<br />

Cl<br />

lesions; developmental and reproductive effects; damage<br />

to the immune system; hormonal disruption; and,<br />

possibly, mild liver damage. The agency is still working<br />

on a second document focusing on cancer hazards<br />

of TCDD.<br />

The assessment, which EPA launched in 1991 to<br />

update a 1985 document describing<br />

the cancer hazards of<br />

TCDD, has faced many delays.<br />

Throughout the years, polluting<br />

industries—including chemical<br />

companies—have faulted EPA’s<br />

work. Community and public<br />

health groups, meanwhile, have pressured the agency<br />

to finish the review.<br />

“After 21 years in the making, the dioxin assessment<br />

is in the hands of the American people,” says Paul T.<br />

Anastas, who oversaw release of the report on his final<br />

day as EPA’s top scientist (C&EN, Jan. 16, page 9).<br />

“I quite honestly never thought this report would<br />

ever see the light of day,” Gibbs says. — CHERYL HOGUE<br />

Backyard burning<br />

of waste is now<br />

the main source of<br />

dioxins, according<br />

to EPA.<br />

SHUTTERSTOCK

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