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Newsletter 02 2006.pdf - Sight and Life

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NEWSLETTER 2/2006<br />

23<br />

SIGHT AND LIFE<br />

13 th European Meeting on Fat-Soluble Vitamins<br />

2006 in Jena<br />

Volker Böhm, PD, Institut für Ernährungswissenschaften, Friedrich-Schiller-Universität<br />

Jena, Germany<br />

This year, for the first time, this<br />

European Conference took place<br />

in Germany. Fat-soluble vitamins<br />

(FSV) offer a wide field of research<br />

<strong>and</strong> have brought together European<br />

scientists <strong>and</strong> students every<br />

three to four years since 1960,<br />

first in the UK <strong>and</strong> then touring<br />

Europe. After Arcachon (1996)<br />

<strong>and</strong> Toulouse (2000) in France<br />

<strong>and</strong> Rieti (2003) in Italy, this year<br />

Jena in Germany provided an opportunity<br />

to listen <strong>and</strong> to lecture,<br />

to discuss <strong>and</strong> to develop stateof-the-art<br />

<strong>and</strong> new approaches,<br />

illuminating the role of these<br />

compounds for human health <strong>and</strong><br />

more. A very efficient interchange<br />

of knowledge took place due to<br />

the traditionally small number of<br />

around 50 participants. Students,<br />

in particular, took this opportunity<br />

to present their work on a European<br />

level <strong>and</strong> to talk to experts<br />

in the field.<br />

The 13 th FSV meeting was hosted<br />

by the Institute of Nutrition at<br />

the renowned Friedrich Schiller<br />

University in Jena. It took place<br />

in the Old Castle in Dornburg<br />

(10 km from Jena), that has just<br />

been completely refurbished to<br />

meet the dem<strong>and</strong>s of a modern<br />

meeting place while keeping its<br />

beautiful historical ambience.<br />

Accommodation was in Jena, a<br />

city of 100,000 inhabitants <strong>and</strong><br />

also famous for its optical trade<br />

(Zeiss, Jenoptik).<br />

The conference started with a<br />

plenary lecture by the internationally<br />

known carotenoid expert<br />

Steven J Schwartz from the Ohio<br />

State University in Columbus,<br />

Ohio, USA. He presented some<br />

of the results of his group on bioavailability<br />

of different carotenoids,<br />

talking also on bioactivity of<br />

these secondary plant products<br />

being able to reduce the risks<br />

for some degenerative diseases.<br />

The first session followed, reporting<br />

results with carotenoids.<br />

Catherine Caris-Veyrat from INRA<br />

Avignon, France, mainly focused<br />

on oxidation products of carotenoids,<br />

discussing some possible<br />

effects of these metabolites. Yoav<br />

Sharoni from Beer-Sheva, Israel,<br />

presented new results on mechanisms<br />

for cancer prevention by<br />

carotenoids, while Gordon Lowe<br />

from Liverpool, UK, explained<br />

investigations on interactions<br />

between cigarette smoke <strong>and</strong><br />

β-carotene.<br />

The second session focussed on<br />

vitamin E. David Muller, London,<br />

UK, presented analytical details<br />

on separation <strong>and</strong> quantification<br />

of conjugated vitamin E metabolites<br />

in sepsis. Andreas Wagner<br />

from Jena, Germany, showed<br />

how intervention with α-tocopherol<br />

<strong>and</strong> folic acid affected 8-<br />

oxodG, a biomarker of oxidative<br />

stress in leukocytes <strong>and</strong> urine<br />

in humans. Stefano Manfredini,<br />

Ferrara, Italy, finished the session,<br />

comparing the antioxidant<br />

activity of novel vitamin E based<br />

antioxidants within several assay<br />

systems. Afterwards most delegates<br />

enjoyed typical Thuringian<br />

sausages, beer <strong>and</strong> jazz music.<br />

The second day started with<br />

results on the structure-activity<br />

relationship of carotenoid derivatives<br />

in activation of the antioxidant<br />

response element transcription<br />

system, presented by Joseph<br />

Levy, Beer-Sheva, Israel. Paola

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