Clinical Approach to Medical Management of Type 2 Diabetes
Clinical Approach to Medical Management of Type 2 Diabetes
Clinical Approach to Medical Management of Type 2 Diabetes
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Metformin: Old Drug, New Targets<br />
Libby et al, <strong>Diabetes</strong> Care, 2009<br />
• Observational Cohort Study<br />
in U.K.<br />
–4085 DM2 on MF<br />
–4085 DM2 compara<strong>to</strong>rs (matched<br />
<strong>to</strong> the yr <strong>of</strong> DM diagnosis)<br />
• Primary outcome:<br />
–Diagnosis <strong>of</strong> Cancer<br />
–297 cases (7.3%) MF group<br />
–474 cases (11.6%) Compara<strong>to</strong>rs<br />
• Secondary outcomes:<br />
– Diagnosis <strong>of</strong> colon, lung,<br />
breast cancer<br />
– All cause and cancer mortality
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