Clinical Approach to Medical Management of Type 2 Diabetes
Clinical Approach to Medical Management of Type 2 Diabetes
Clinical Approach to Medical Management of Type 2 Diabetes
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Treat <strong>to</strong> Target in <strong>Type</strong> 2 <strong>Diabetes</strong> Trial<br />
• 708 patients not controlled<br />
with MF or SU<br />
• Duration – 3 years<br />
• Baseline A1c 8.3%<br />
• Treatment groups:<br />
– Basal insulin QD/BID (detemir)<br />
– Prandial insulin TID (aspart)<br />
– Biphasic insulin BID/TID<br />
(NovologMix 70/30)<br />
A1c 6.9%<br />
Holman et al, NEJM, 2009