Clinical Approach to Medical Management of Type 2 Diabetes
Clinical Approach to Medical Management of Type 2 Diabetes
Clinical Approach to Medical Management of Type 2 Diabetes
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Adjusted Hazard Ratio for <strong>Clinical</strong> Events in<br />
ADVANCE Trial<br />
End Point<br />
Major<br />
Macrovascular Event<br />
Major Microvascular<br />
Event<br />
Severe Hypoglycemia,<br />
N=231, (%)<br />
No Severe<br />
Hypoglycemia,<br />
N=10909, (%)<br />
HR (95% CI)<br />
15.9 10.2 3.5 (2.4-5.1)<br />
11.5 10.1 2.2 (1.4-3.4)<br />
All Cause Mortality 19.5 9.0 3.3 (2.3-4.6)<br />
Cardiovascular<br />
Mortality<br />
Noncardiovascular<br />
Mortality<br />
9.5 4.8 3.8 (2.4-6)<br />
10 4.3 2.8 (1.6-4.8)<br />
Zoungas et al, NEJM, 2010
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