2007 Annual Report - College of Pharmacy - The Ohio State University

Badawy SIF, Gray DB, Zhao F, Sun D, Schuster AE, Hussain MA. Formulation of Solid Dosage Forms to
Overcome Gastric pH Interaction of the Factor Xa Inhibitor, BMS-561389. Pharm Res, 2006, 23, 989-996.
Nadas J and Sun D. Anthracyclines as effective anticancer drugs. Expert Opinion on Drug Discovery, 2006, 1:549-
568.
Cao X, Gibbs ST, Fang L, Miller HA, Landowski CP, Shin H-C, Lennernas H, Zhong Y, Amidon GL, Yu LX,
and Sun D. Why is it Challenging to Predict Intestinal Drug Absorption and Oral Bioavailability in Human
Using Rat Model. Pharm Res, 2006, 23: 1675-1686.
Fang L, Battisti RF, Cheng H, Reigan P, Xin Y, Shen J, Ross D, Chan KK, Martin Jr EW, Wang PG, and Sun D.
Enzyme Specific Activation of Benzoquinone Ansamycin Prodrugs Using Humanized HuCC49CH2-alpha-
Galactosidase Conjugates. J Med Chem, 2006, 49: 6290-6297.
Division of Pharmacology
Affara, N.I., Trempus, C.S., Schanbacher, B.L., Pei, P., Mallery, S.R., Bauer, J.A., Robertson, F.M., “Activation of
Akt and mTOR in CD34+/K15+ keratinocyte stem cells and skin tumors during multi-stage mouse skin
carcinogenesis”. Anticancer Research 26(4B): 2805-20, Jul-Aug 2006.
Giannone, P.J., Bauer, J.A., Schanbacher, B.L., Reber, K.M., “Effects of hyperoxia on postnatal intestinal
development”. Biotechnic Histochemistry: 82(1): 17-22, 2007.
Groner, J.A., Joshi, M., Bauer, J.A., “Pediatric precursors of adult cardiovascular disease: noninvasive assessment
of early vascular changes in children and adolescents”. Pediatrics 118(4): 1683-91, Oct. 2006.
Mihm MJ, Amann DM, Schanbacher BL, Altschuld RA, Bauer JA, Hoyt KR. “Cardiac dysfunction in the R6/2
mouse model of Huntington’s disease.” Neurobiology of Disease 25(2):297-308, 2007.
Giannone, P.J., Schanbacher, B.L., Bauer, J.A., Reber, K.M., “Effects of prenatal lipopolysaccharide exposure on
epithelial development and function in newborn rat intestine”. Journal of Pediatric Gastroenterology and Nutrition
43(3): 284-90, Sep, 2006.
Mihai, C., Iscru, D.F., Druhan L.J., Elton, T.S., Agarwal, G. “Discoidin domain receptor 2 inhibits fibrillogenesis
of collagen type 1”. Journal of Molecular Biology 361(5):864-76, 2006.
Martin, M.M., Lee, E.J., Jiang, J. Buckenberger, J.A., Schmittgen, T.D. and T.S. Elton. “MicroRNA-155
regulates human angiotensin II type 1 receptor expression in fibroblasts.” Journal of Biological Chemistry
281(27):18277-84, 2006.
Sridhar, A., Dech, S., Lacombe, V., Elton, T., McCune, S., Altschuld, R. and Carnes, C. “Abnormal diastolic
currents in ventricular myocytes from spontaneous hypertensive and heart failure (SHHF) rats.” AJP-Heart and
Circulatory Physiology 291(5):H2192-98, 2006.
Carrier RL, Ma TC, Obrietan K, Hoyt KR. “A sensitive and selective assay of neuronal degeneration in cell
culture.” Journal of Neuroscience Methods 154:239-44, 2006.
Ma TC, Buescher JL, Oatis B, Funk JA, Nash AJ, Carrier RL, Hoyt KR. “Metformin therapy in a transgenic
mouse model of Huntington’s disease.” Neuroscience Letters 411(2):98-103, 2007.
Rose, JL, Reeves, KC, Likhotvorik, RI, Hoyt, DG: “Base excision repair proteins are required for integrinmediated
suppression of bleomycin-induced DNA breakage in murine lung endothelial cells” J Pharmacol Exp
Ther 321(1): 318-26, 2007
McKay, D.B., Chang, C., González-Cestari, T.M., McKay, S.B., El-Hajj, R.A., Bryant, D.L., Zhu, M.X., Swaan,
P.W., Arason, K.M., Pulipaka, A.B., Orac, C.M., and Bergmeier, S.C. “Analogs of methyllycaconitine as novel
noncompetitive inhibitors of nicotinic receptors: pharmacological characterization, computational modeling, and
pharmacophore development.” Molecular Pharmacology 71(5):1288-97, 2007.
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