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Background: Cytoadherence<br />
Erythrocyte (Red Blood Cell) Infection<br />
• P. falciparum infected erythrocytes (IE’s) exhibit cytoadherence<br />
(stick to blood vessel walls /endo<strong>the</strong>lium).<br />
• Prevents IE elimination by <strong>the</strong> spleen and causes vascular blockages.<br />
• Interaction with endo<strong>the</strong>lium surface receptors (eg. CD36).<br />
Adapted from http://cmr.asm.org/cgi/content-nw/full/13/3/439/F1.<br />
Adapted from <strong>the</strong> Plasmodium Genome Resource.<br />
1/22/2013<br />
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