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Vol 41 # 3 September 2009 - Kma.org.kw

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216<br />

External Non-Invasive Cardiac Pacemaker: Evaluation of Usefulness, Function and Capture...<br />

<strong>September</strong> <strong>2009</strong><br />

PATIENTS AND METHODS<br />

Study patients:<br />

Initially we enrolled 162 patients with<br />

symptomatic bradycardia or asystolic cardiac<br />

arrest but only 140 patients (124 male and 16<br />

female) with a mean age of 55.3 ± 6.4 years were<br />

included in the study. Twenty-two patients were<br />

excluded due to incomplete data. All patients were<br />

admitted in the coronary care unit (CCU) of the<br />

department of medicine with hemodynamically<br />

significant bradyarrhythmias between January 1997<br />

and <strong>September</strong> 2004. All patients were evaluated<br />

clinically by looking at history, physical examination,<br />

12-leads ECG, chest X-ray, routine laboratory<br />

investigations and echocardiography and Doppler<br />

study. Thirty- eight patients had type 2 diabetes<br />

mellitus but no patient had ketoacidosis. Twentythree<br />

patients had history of chronic obstructive<br />

pulmonary disease (COPD). Twenty-six patients<br />

had history of coronary artery bypass graft (CABG)<br />

surgery with post-sternotomy scar. The study was<br />

approved by the hospital ethical committee.<br />

Methods:<br />

We trained all CCU nursing staff to perform<br />

transcutaneous pacing in one to two-hour classes.<br />

Informed consent was obtained from patients for<br />

insertion of intravenous temporary pacemaker (ITP)<br />

if necessary.<br />

Pacing devices:<br />

Three different new pacemaker devices were used<br />

in the study and all were devices of the modified<br />

version which was introduced in 1983 [8] .<br />

1. CardioMaster device in 48 patients<br />

2. CardioLife device in 40 patients<br />

3. CardioServe device in 52 patients<br />

The NTP consists of an electric cardiac pacemaker<br />

combined with a cardiac monitor and a paper<br />

recorder. The pacemaker monitor senses voltage<br />

changes of appropriate amplitude and slew rate<br />

from cardiac depolarizations or pacemaker stimuli.<br />

It provides audible and visual signals of such events<br />

with oscilloscopic and paper recordings, displays<br />

their rate and rings an alarm if selected limits are<br />

exceeded. The pacemaker functions in the demand<br />

mode (VVI), emitting stimuli that are synchronized<br />

to the sensed electrical signals at escape rates up to<br />

180 beats/minute and an amplitude upto 140 mA.<br />

Large stimulating electrodes of high impedance<br />

are placed on the apex and at right upper border<br />

of the sternum and monitor leads are attached. The<br />

pacemaker output is lowered to zero and the power is<br />

turned on. The pacemaker amplitude is then increased<br />

until a stimulated QRS-T response follows the artifact<br />

immediately and suppresses any intrinsic complex<br />

that might fall in its refractory period (Fig. 1). The<br />

Fig. 1: Bradycardiac patient with signs of hypoperfusion. The<br />

demand pacemaker (VVI) was attached to the patient and the<br />

current was raised until capture.<br />

stimulus amplitude is kept just above this stimulation<br />

threshold. In emergency situations, stimulation may<br />

be started within seconds.<br />

Treatment protocol:<br />

Asystolic cardiac arrest patients: Asystole is<br />

defined as the absence of electrical activity greater<br />

than 1 mm (calibrated to 10 mm per millivolt) for at<br />

least 15 seconds [10] . Cardiopulmonary resuscitation<br />

was started immediately with endotracheal<br />

intubation by an anesthetist followed by placing of<br />

transcutaneous NTP leads and adjusting the current<br />

for capturing the heart myocardium.<br />

Symptomatic bradycardia patients: Patients with<br />

hemodynamically significant sinus bradycardia,<br />

complete heart block with idioventricular rhythm and<br />

escape junctional rhythm were indicated for NTP.<br />

Evaluation of pacemaker capture:<br />

1. Carotid pulse rate and volume: by palpating right<br />

or left common carotid artery in the neck between<br />

medial border of the sternomastoid muscle and the<br />

trachea<br />

2. Blood pressure response: non-invasive<br />

measurement of BP by an electronic device<br />

3. Monitor rhythm: as detected on cardiac monitor<br />

screen display<br />

4. Echocardiogram: transthoracic parasternal long<br />

and short axis views were obtained to detect<br />

presence or absence of myocardial wall motion<br />

as an indication of proper electrical capture of the<br />

NTP stimulation<br />

Collection of data and clinical outcomes:<br />

1. Variables related to the emergency device such as<br />

type of external pacemaker, current (mA), pulse<br />

duration (msec) and pacing electric capture<br />

2. Variables related to the hemodynamically significant<br />

bradycardia patients such as etiology, diagnosis

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