Antibody Engineering Conference, San Diego - MorphoSys
Antibody Engineering Conference, San Diego - MorphoSys
Antibody Engineering Conference, San Diego - MorphoSys
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CDR-H3 Length Distribution<br />
� Twelve different CDR-<br />
H3 lengths ranging<br />
from 6 to 17 amino<br />
acids<br />
� Covering 80% of the<br />
natural human CDR-H3<br />
diversity (according to<br />
Zemlin et al., 2003)<br />
� Lengths 6 to 17:<br />
JH4 specific design<br />
� Lengths 12 to 17:<br />
additional JH6 specific<br />
design<br />
Page 20 2011 <strong>Antibody</strong> <strong>Engineering</strong><br />
© <strong>MorphoSys</strong> AG
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