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Antibody Engineering Conference, San Diego - MorphoSys

Antibody Engineering Conference, San Diego - MorphoSys

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Biophysical Properties of Selected Antibodies<br />

IgG1 Production Yields<br />

More than 95% of the antibodies express more than 10 mg IgG1 per liter in a three<br />

day transient mammalian expression culture as determined after purification.<br />

Average production yields: ~25 mg/L.<br />

� Human IgG1 antibodies<br />

were transiently expressed<br />

for 3 days in HKB11 cells<br />

in shake flasks and<br />

purified via Protein A.<br />

Page 30 2011 <strong>Antibody</strong> <strong>Engineering</strong><br />

© <strong>MorphoSys</strong> AG

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