colonies
colonies
colonies
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2<br />
Cells within multicellular <strong>colonies</strong> differentiate and<br />
undergo regulated cell death<br />
<br />
What is approximate position of cells within colony during its development <br />
Alexa Fluor® 488 5-TFP<br />
• During their division, cells are not<br />
pushed in horizontal direction but remain<br />
approximately at their original location.<br />
Centre: mostly older, chronologically<br />
ageing cells<br />
Outer colony margin: relatively young,<br />
infant cells.<br />
<br />
What are the changes in cells in the center and in newly grown<br />
margin at different times of colony development.<br />
<br />
Changes connected with yeast cell dying <br />
Váchová & Palkova., J. Cell. Biol. 169, 711–717, 2005
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