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IN NATURE<br />

IN LABORATORY<br />

Extracellular<br />

matrix<br />

raining<br />

drying<br />

Relatively stable humidity<br />

Limited concentration of nutrients<br />

Temperature fluctuations<br />

Small “channels“ enable better flow<br />

of water, nutrients, waste products<br />

Initial high concentration of nutrients<br />

Standard temperature<br />

DOMESTICATION<br />

Stop of the production of extracellular matrix material and extensive changes in<br />

gene expression<br />

A complex change of the yeast life-style during the<br />

nature ⇒ laboratory transfer

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