colonies
colonies
colonies
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PRO-APOPTOTIC MARKERS<br />
ROS<br />
(DHE)<br />
ASPase<br />
(D 2<br />
R)<br />
DNA breaks<br />
(TUNEL)<br />
Phosphatidyl<br />
serine<br />
relocalisation<br />
(Annexin)<br />
Chromatine<br />
fragmentation<br />
(DAPI)<br />
Cell<br />
morphology<br />
(Nomarski)<br />
ROS<br />
Early proapoptotic<br />
markers<br />
Parental<br />
strain<br />
<strong>colonies</strong><br />
Healthy cells<br />
Late proapoptotic<br />
markers<br />
Parental<br />
strain<br />
<strong>colonies</strong><br />
Colonies of<br />
sok2 mutant<br />
ROS<br />
Early proapoptotic<br />
markers<br />
Colonies of<br />
sok2 mutant<br />
Late proapoptotic<br />
markers<br />
Late acidic phase<br />
Alkali<br />
/ weak alkali phase
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