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Paterson Institute for Cancer Research SCIENTIFIC REPORT 2005

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J.L., van Zandwijk, N., Gridelli, C., van Meerbeeck,<br />

J.P., Crino, L., Brown, A., Fitzgerald, P., Aristides,<br />

M. and Schiller, J.H. (<strong>2005</strong>) Efficacy of gemcitabine<br />

plus platinum chemotherapy compared with other<br />

platinum containing regimens in advanced nonsmall-cell<br />

lung cancer: a meta-analysis of survival<br />

outcomes. Lung <strong>Cancer</strong>, 47, 69-80.<br />

Swaisland, H.C., Ranson, M., Smith, R.P.,<br />

Leadbetter, J., Laight, A., McKillop, D. and Wild,<br />

M.J. (<strong>2005</strong>) Pharmacokinetic drug interactions of<br />

gefitinib with rifampicin, itraconazole and metoprolol.<br />

Clin Pharmacokinet, 44, 1067-1081.<br />

Swaisland, H.C., Smith, R.P., Laight, A., Kerr, D.J.,<br />

Ranson, M., Wilder-Smith, C.H. and Duvauchelle,<br />

T. (<strong>2005</strong>) Single-dose clinical pharmacokinetic studies<br />

of gefitinib. Clin Pharmacokinet, 44, 1165-1177.<br />

Valle, J.W., Dangoor, A., Beech, J., Sherlock, D.J.,<br />

Lee, S.M., Scarffe, J.H., Swindell, R. and Ranson, M.<br />

(<strong>2005</strong>) Treatment of inoperable hepatocellular carcinoma<br />

with pegylated liposomal doxorubicin<br />

(PLD): results of a phase II study. Br J <strong>Cancer</strong>, 92,<br />

628-630.<br />

Ward, T.H., Danson, S., McGown, A.T., Ranson,<br />

M., Coe, N.A., Jayson, G.C., Cummings, J.,<br />

Hargreaves, R.H. and Butler, J. (<strong>2005</strong>) Preclinical<br />

evaluation of the pharmacodynamic properties of<br />

2,5-diaziridinyl-3-hydroxymethyl-6-methyl-1,4-benzoquinone.<br />

Clin <strong>Cancer</strong> Res, 11, 2695-2701.<br />

Other publications<br />

Danson, S., Blackhall, F., Hulse, P. and Ranson, M.<br />

(<strong>2005</strong>) Interstitial lung disease in lung cancer: separating<br />

disease progression from treatment effects.<br />

Drug Saf, 28, 103-113.<br />

Ranson, M. and Jayson, G. (<strong>2005</strong>) Targeted antitumour<br />

therapy—future perspectives. Br J <strong>Cancer</strong>, 92<br />

Suppl 1, S28-31.<br />

____________________________________<br />

GENE THERAPY GROUP (page 24)<br />

Lez Fairbairn<br />

Refereed <strong>Research</strong> Papers<br />

Atkinson, D.E., Sibley, C.P., Fairbairn, L.J. and<br />

Greenwood, S.L. (<strong>2005</strong>) MDR1 P-gp expression<br />

and activity in intact human placental tissue; upregulation<br />

by retroviral transduction. Placenta, epub<br />

Aug 05.<br />

Green, K.L., Southgate, T.D., Mulryan, K.,<br />

Fairbairn, L.J., Stern, P.L. and Gaston, K. (<strong>2005</strong>)<br />

Diffusible VP22-E2 Protein Kills Bystander Cells<br />

and Offers a Route <strong>for</strong> Cervical <strong>Cancer</strong> Gene<br />

Therapy. Hum Gene Ther, epub Dec 05.<br />

Milsom, M.D., Duxbury, R., Gagen, D., Humphries,<br />

R.K., Schmidt, M., von-Kalle, C. and Fairbairn, L.J.<br />

(<strong>2005</strong>) Overexpression of HOXB4 confers a<br />

myelo-erythroid differentiation delay in vitro.<br />

Leukemia, 19, 148-153.<br />

Wool<strong>for</strong>d, L.B., Southgate, T.D., Margison, G.P.,<br />

Milsom, M.D. and Fairbairn, L.J. (<strong>2005</strong>) The P140K<br />

mutant of human O6-methylguanine-DNA-methyl transferase (MGMT) confers resistance in vitro and<br />

in vivo to temozolomide in combination with the<br />

novel MGMT inactivator O6-(4-bromothenyl)gua nine. J Gene Med, epub Aug 05, printed 2006, 8, 29-<br />

34.<br />

P A T E R S O N I N S T I T U T E S C I E N T I F I C R E P O R T 2 0 0 5<br />

59

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