Paterson Institute for Cancer Research SCIENTIFIC REPORT 2005

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74 Career Opportunities The Paterson Institute is located alongside the Christie Hospital, and has a strong programme of basic and translational research. There are very close links with clinical and translational research groups throughout the Christie Hospital site. New developments are in progress to create a Manchester Cancer Research Centre with partners including the Paterson Institute, the Christie Hospital NHS Trust, the University of Manchester and Cancer Research UK. This is an extremely exciting development which will enhance all aspects of cancer research, education and treatment. The Institute offers excellent laboratory facilities and outstanding core facilities, including molecular services, a microarray platform, proteomics, the production of knock-in/knock-out animal models, real-time PCR and advanced imaging. Details of all groups and facilities are given throughout this report, and can guide interested parties to the appropriate contacts. Opportunities exist at a number of levels in the Institute. We have a well-established programme of degrees by research which is described in the section on Postgraduate Education (page 68). We encourage applications from suitable qualified graduates to apply to join either the PhD or MD programmes. Graduates with a first or 2.1 honours degree in a biological science can apply each year to train for a four-year PhD in one of our research laboratories. First year students will compliment their laboratory skills by attending a small number of specialised postgraduate taught and training courses allowing them to gain a sound knowledge base of the latest developments in cancer treatment and research. The Institute also has a well developed process for ensuring suitable pastoral care and mentoring for all students. Postdoctoral applicants of high calibre are regularly sought. Although post docs will be encouraged to apply for their own fellowships, funded positions are always available for outstanding candidates. Interested applicants should contact the Group Leaders directly, with details of their area of interest and recent experience. Links to sources of potential funding for fellowships are provided on http://www.paterson.man.ac.uk/djs?jid=222. In addition to postgraduate and postdoctoral opportunities, the Institute is still seeking to recruit outstanding candidates to the positions of Junior and Senior Group Leaders. The packages provided are extremely attractive and commensurate with the experience of the applicant, with significant funding for personnel, recurrent expenditure and equipment. Junior Group Leaders are appointed for an initial six-year period, with Senior Group Leaders appointed to non-time limited positions Specific vacancies can be found on our web pages (http://www.paterson.man.ac.uk/vacancies), but suitably qualified and enthusiastic individuals should contact the Institute at any time to enquire about career possibilities. P A T E R S O N I N S T I T U T E S C I E N T I F I C R E P O R T 2 0 0 5 The Manchester Wheel. (Photograph courtesy of Adam Dangoor)
How to Find Us The Paterson is well placed for both national and international travel, with Manchester Airport only around a 30 minute drive away. The region is very well-served by the motorway network and the West Coast mainline rail service Palatine Road Visitors Car Park MAIN HOSPITAL ENTRANCE OUT-PATIENT ENTRANCE NATHAN HOUSE PRIVATE PATIENTS UNIT ENTRANCE PATERSON INSTITUTE ENTRANCE
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Paterson Institute for Cancer Resea
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Cancer Research UK Paterson Institu
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5 Contents Director’s Introductio
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espect with his peers. He enjoyed l
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BIOINFORMATICS age, MIAME VICE is b
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CARCINOGENESIS Clinical trials invo
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CELL CYCLE the RPC contains a two-s
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CELL DIVISION Plo1 regulated its af
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CELL REGULATION inactivation of ATF
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CELL SIGNALLING One probable mechan
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CELLULAR AND MOLECULAR PHARMACOLOGY
Page 23 and 24: CLINICAL AND EXPERIMENTAL PHARMACOL
Page 25 and 26: GENE THERAPY ued our studies utilil
Page 27 and 28: IMMUNOLOGY tory cells following tum
Page 29 and 30: MITOTIC SPINDLE FUNCTION & CELL CYC
Page 31 and 32: RADIOCHEMICAL TARGETING AND IMAGING
Page 33 and 34: STEM CELL BIOLOGY their potential w
Page 35 and 36: STEM CELL AND HAEMATOPOIESIS Import
Page 37 and 38: STRUCTURAL CELL BIOLOGY NE disperse
Page 39 and 40: ACADEMIC RADIATION ONCOLOGY: TRANSL
Page 41 and 42: MEDICAL ONCOLOGY: BREAST BIOLOGY me
Page 43 and 44: MEDICAL ONCOLOGY: GENE-IMMUNOTHERAP
Page 45 and 46: MEDICAL ONCOLOGY: GLYCOANGIOGENESIS
Page 47 and 48: MEDICAL ONCOLOGY: PROTEOGLYCAN GROU
Page 49 and 50: CANCER STUDIES: TARGETED THERAPY ne
Page 51 and 52: RESEARCH SERVICES To achieve these
Page 53 and 54: RESEARCH SERVICES The media and pla
Page 55 and 56: RESEARCH SERVICES successful pilot
Page 57 and 58: Patents O 6 -Substituted guanine de
Page 59 and 60: J.L., van Zandwijk, N., Gridelli, C
Page 61 and 62: Gillies, J.M., Najim, N. and Zweit,
Page 63 and 64: Clarke, R.B. and Bundred, N.J. (200
Page 65 and 66: Jayson, G.C., Mulatero, C., Ranson,
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Page 69 and 70: POSTGRADUATE EDUCATION students to
Page 71 and 72: ADMINISTRATIVE SERVICES The team ha
Page 73: Donations to the Institute in 2005
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Paterson Institute for Cancer Research SCIENTIFIC REPORT 2005

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