POSTER ABSTRACTS <strong>SAGES</strong> <strong>2005</strong> pathophysiology of this phenomenon remains unclear and it will require further research to establish it. Preoperative manometric evaluation for fundoplication is a controversial issue but it is also the gold standard to recognize esophageal motor disorders. It also helps identify esophageal motor disorders whether they were, or not present preoperatively for legal purpose. P252–Esophageal/Gastric Surgery THE ROLE OF SELECTIVE VAGOTOMY DURING NISSEN FUN- DOPLICATION, S Dissanaike MD, K O Shebani MD,E E Frezza MD, Texas Tech University Health Sciences Center After Laparoscopic Nissen fundoplication, some patients continued to experience symptoms related to high acid output. To alleviate this problem, we decided to perform selective vagotomy on those patients who complained of epigastric pain, a pain consistent with peptic ulcer disease, or who have had a history of peptic ulcer disease. METHODS We prospectively studied all patients who came to see us with gastroesophageal reflux disease GERD, a history of peptic ulcer disease or associated gastritis. The patients were assigned to two treatment groups: 1) Nissen fundoplication (NF) only and 2) NF with highly selective vagotomy (HSV). Patients were selected for HSV based on: 1) high acid output, 2) pre-prandial pain, 3) history of peptic ulcer, 4) high dose protein pump inhibitor therapy and 5) failure of anti-acid therapy after 6 months. Prior to the operation, an upper endoscopy was performed to rule out acute peptic ulcer or gastritis. A 24 hour pH study and manometry were also performed. RESULTS Three patients in each group were considered in our initial series. The mean age was 41 +/- 8 in the first group and 44 +/- 9 in the second. Patients were on anti-acid therapy for an average of 12 +/- 4 months in the first group and 10 +/- 3 months in the second group. There were no active peptic ulcers or active gastritis in either group. Esophagitis was present in both groups. Manometry was normal. The DeMeester score was slightly higher in the second group. Operative time was 90 +/- 20 minutes for group 1 and 110 +/- 15 minutes for group 2. None of the patients complained of reflux. In group 1, 2 out of 3 patients were re-started on anti-acid therapy, with some relief of symptoms. In group 2, no patients complained of stomach pain or required anti-acid therapy. CONCLUSION Adding HSV to the Nissen fundoplication decreased the symptomatology of high acid production. More studies are needed before a final conclusion can be drawn. From our preliminary data, we feel that performing HSV can be advantageous to the patient, adding only 15 to 20 minutes to the procedure. P253–Esophageal/Gastric Surgery LAPAROSCOPIC GASTRIC BYPASS ? AN EFFECTIVE TREAT- MENT FOR COMPLICATED GERD. A CASE REPORT., Piotr Gorecki MD, Kevin Cho MD,Katherine Martone MD,Leslie Wise MD, Department of Surgery, New York Methodist Hospital, Brooklyn, NY Introduction: Surgical treatment of severe complicated gastroesophageal reflux disease (GERD) associated with a large hiatal hernia remains a challenging problem. High incidence of symptoms recurrence has been reported after laparoscopic repair. Case report: A 29 year- old morbidly obese female suffering from severe heartburn, regurgitation and dysphagia presented for evaluation for weight reduction surgery. Her weight was 234 lbs and BMI was 40 kg/m2. Her quality of life was significantly impaired because of her symptoms. Her preoperative evaluation revealed esophagitis with a 6 cm hiatal hernia and stricture of the distal esophagus. A 24-h pH testing revealed a significant acid exposure of the distal esophagus with DeMeester score of 177. Esophageal manometry revealed hypotensive low esophageal sphincter (LES) with LES pressure of 1 mm Hg. The patient underwent endoscopic balloon dilatation of the esophageal stricture followed by a course of aggressive treatment of esophagitis with proton pump inhibitors for three months. Her dysphagia improved. She underwent a laparoscopic reduction of a large hiatal hernia with high mediastinal dissection to establish intraabdominal 192 http://www.sages.org/ segment of the short esophagus and a Roux-en Y gastric bypass. Her recovery was uneventful and she was discharged home on a fourth postoperative day. At four-month follow up visit she reported complete resolution of her reflux and dysphagia symptoms and no need for acid suppresion medications. She enjoyed weight loss of 47 lbs and her quality of life improved from not acceptable to excellent. Radiograms and endoscopy photographs will be presented. Conclusion: Aggressive treatment of esophagitis and preoperative balloon dilatation of peptic stricture followed by laparoscopic repair of hiatal hernia and Roux Y gastric bypass is feasible and may be considered as the most definite surgical treatment of severe GERD complicated by esophageal stricture. P254–Esophageal/Gastric Surgery LESSONS LEARNED FROM LAPAROSCOPIC TREATMENT OF ESOPHAGEAL AND GASTRIC SPINDLE CELL TUMORS, Steven R Granger MD, Michael D Rollins MD,Sean J Mulvihill MD,Robert E Glasgow MD, Department of Surgery, University of Utah Medical Center, Salt Lake City, Utah, USA Introduction: Gastric and esophageal spindle cell tumors are rare neoplasms that have been traditionally resected for negative margins through an open approach. The aim of this study was to evaluate the efficacy and lessons learned from laparoscopic resection of gastric and esophageal spindle cell tumors. Methods and Procedures: This was a retrospective review of all patients who underwent laparoscopic resection of gastric or esophageal spindle cell tumors at a tertiary referral center between December 2002 and August 2004. Medical records were reviewed with regard to patient demographics, preoperative evaluation, operative approach, tumor location and pathology, length of operation, complications, and length of hospital stay. Results: Ten consecutive patients (6 men and 4 women) with a mean±SEM age of 51±6.2 years (range, 21-72) were treated. Preoperative endoscopic ultrasound (EUS) was performed in all patients with a diagnostic accuracy of 100% for predicting spindle cell neoplasm, while EUS-guided FNA had a diagnostic accuracy of 55% in correctly predicting the final pathology. R0 laparoscopic resection was achieved in all patients. Four patients with symptomatic distal esophageal leiomyomas were treated with enucleation and Nissen fundoplication. Six patients were treated with laparoscopic wedge resection of gastric lesions which included leiomyoma (1), GIST (3), and heterotopic pancreas (2). Intraoperative endoscopy was performed in 4 patients and was associated with shorter operative times (161±21.7 versus 196±24.2 without intraoperative endoscopy). Operative time for this whole series was 182±17 minutes, 197±28 minutes for the first 5 cases and 167±19 minutes for the last 5 cases. The mean length of hospital stay was 2.1±0.25 days. One patient with esophageal leiomyoma had persistent dysphagia at 12 month follow-up. There were no other complications and no deaths in this series of patients. Conclusions: Laparoscopic resection of esophageal and gastric spindle cell tumors may be performed safely with low patient morbidity. This approach can accomplish adequate surgical margins and lead to short hospital stays. Improvements in technique have led to shorter operative times. P255–Esophageal/Gastric Surgery SYMPTOMATIC OUTCOMES AFTER LAPAROSCOPIC MODI- FIED HELLER MYOTOMY AND DOR FUNDOPLICATION (MHMDF) FOLLOWING FAILED MEDICAL MANAGEMENT OF ACHALASIA., Mohammad K Jamal MD, Eric J DeMaria MD,Alfredo M Carbonell DO,Jason M Johnson DO,Brennan J Carmody MD, Department of Surgery, Virginia Commonwealth University, Richmond, Virginia. Patients with failed non-operative management of achalasia may have suboptimal outcomes after MHMDF. We report a single surgeon experience in 30 patients with achalasia who underwent a MHMDF between 1998 and 2004. The aim of the study was to determine the impact of pre-operative treatment on a detailed symptom assessment. Pre- and post-operative symptom scoring (SS) was obtained using a standard questionnaire. Patients were asked to quantitate their symptoms in 6 categories on a scale of 0 to 3 (0=none, 1=mild, 2=moderate,
POSTER ABSTRACTS 3=severe). A total SS was calculated as the sum of scores in all 6 categories. The male:female ratio was 1.14:1 and mean age of 46 years. The mean duration of symptoms was 48 months and during this time 80% of patients failed non-operative treatments including botox (n=1), dilatation (n=12) or combined treatment (n=11). Three patients had sigmoid esophagus on contrast study. Only 6 patients did not receive any pre-operative treatment and underwent MHMDF as a first line therapy. Some form of pre-operative testing was carried out in all patients and included manometry (n=17), upper gastro-intestinal series (n=28) and upper endoscopy (n=29). Post-operative contrast studies were performed in all patients. MHMDF was completed laparoscopically in 29/30 patients. There was one esophageal perforation necessitating an open conversion and no mortality in the group. All patients regardless of pre-operative therapy showed improvement in their post-operative dysphagia scores. The total SS decreased significantly from pre- to post-operatively in patients without previous treatment (8.3 ± 3.8 vs. 1.3 ± 1.2, p
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