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2005 SAGES Abstracts

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POSTER ABSTRACTS<br />

Esophageal aperistalsis and simultaneous contractions waves<br />

were observed in all cases. LES resting pressure was normal<br />

in 79.5% of patients, hypertonic in 16.9% and hypotonic in<br />

3.6%. LES segment was from 3 to 5 cms. in 66.1%, and shorter<br />

in 33% of cases. We observed LES lack of relaxation in 2.5% of<br />

patients, relaxation was incomplete in 87.5% and total in only<br />

10%.<br />

Manometric criteria in achalasia diagnosis have changed.<br />

Despite Achalasia means lack of relaxation regarding the LES.<br />

And that historically it was considered that LES should be<br />

hypertonic in this disease. We found these criteria to be not<br />

constant. Nowadays there are mandatory manometric criteria<br />

for the diagnosis of achalasia (ESOPHAGEAL PRIMARY PERI-<br />

STALSIS REPLACEMENT BY SIMULTANEUS WAVES<br />

?ESOPHAGEAL APERISTALSIS?) since it is found constantly.<br />

And there are non obligated manometric criteria for diagnosis<br />

of this disease as the LES findings.<br />

P299–Flexible Diagnostic &<br />

Therapeutic Endoscopy<br />

ESOPHAGEAL DIFFUSE SPASM. A MOTOR PATTERN THAT<br />

PRECEDE ACHALASIA, Jose J Herrera MD, Edgardo Suarez<br />

MD,Maria E Lopez MD,Hiosadhara E Fernandez MD,Jose A<br />

Palacios MD, Hospital Español de México gastrointestinal<br />

motility and endoscopy unit. Hospital General ?Dr. Manuel Gea<br />

González?, gastrointestinal motility and general surgery division.<br />

Esophageal diffuse spasm is a rare motor disorder characterized<br />

for chest pain, dysphagia and segmentarial wave contractions.<br />

Pathophysiology and natural history remains unclear<br />

and it has been suggested that it could precede achalasia. In<br />

both entities the proposed pathophysiology is a Nitric oxide<br />

neuromuscular defect. Manometric findings for diffuse<br />

esophageal spasm are simultaneous wave contractions over<br />

30mmHg amplitude in more than 10% of swallows and for<br />

achalasia the absence of peristalsis is the mandatory manometric<br />

finding.<br />

Aim: To present a patient whom has an initial diagnosis of diffuse<br />

esophageal spasm who in further evaluation had a vigorous<br />

esophageal achalasia.<br />

Case report: We present a 41 years female who came in 2003<br />

with last 3 months progressive dysphagia, heartburn, 5kgs<br />

weight lost, chest pain and hiccups. On first evaluation the<br />

barium esophagogastric evaluation showed esophageal dilation<br />

with bird peak distal segment. EGD revealed dilated<br />

esophagus with remanent food in the esophagus. The manometric<br />

findings were compatible with diffuse esophageal<br />

spasm. Patient was discharged with medical treatment but 7<br />

months alter she came in again because of continuous vomiting,<br />

severe dysphagia, and 12 kgs weight lost. In this new<br />

evaluation the EGD revealed no organic obstruction, dilated<br />

esophagus, and remanent food in it. The manometric pattern<br />

in this new evaluation was compatible with esophageal vigorous<br />

achalasia. The patient went under Heller miotomy with<br />

partial fundoplication.<br />

Manometric findings: First manometric study showed effective<br />

primary peristalsis replacement with simultaneous waves in<br />

40% of swallows. Second manometric study showed effective<br />

primary peristalsis replacement with simultaneous waves in<br />

100% of swallows, with amplitude waves greater than<br />

30mmHg.<br />

Conclusion: Pathophysiology and natural history of<br />

esophageal diffuse spasm remains unclear. Hypersensitivity to<br />

cholinergic stimulus as in achalasia has been observed. It has<br />

been suggested that progression from esophageal diffuse<br />

spasm could precede achalasia in 2 to 5% of cases.<br />

P300–Flexible Diagnostic &<br />

Therapeutic Endoscopy<br />

EFFICACY OF ENDOLUMINAL GASTROPLICATION FOR GAS-<br />

TROESOPHAGEAL REFLUX DEVELOPED AFTER LYMPH<br />

NODES DISSECTION ALONG THE LESSER CURVATURE OF<br />

THE STOMACH, Hitoshi Idani MD, Takashi Ishikawa<br />

MD,Takayuki Iwamoto MD,Masahiko Muro MD,Tatsuaki Ishii<br />

MD,Masahiko Maruyama MD,Shinichiro Kubo MD,Hiroki<br />

Nojima MD,Shinichiro Watanabe MD,Hitoshi Kin MD,<br />

Fukuyama City Hospital, Department of Surgery<br />

Introduction: Endoluminal gastroplication (ELGP) is one of the<br />

newly developed endoscopic treatments for gastroesophageal<br />

reflux disease (GERD). However, its efficacy has been demonstrated<br />

only for primary GERD and there have been no reports<br />

on ELGP for post-surgical GERD. In this paper, we report a<br />

case of GERD developed after perigastric lymph nodes dissection<br />

successfully treated by ELGP.<br />

Case report: 75 year-old man presented with heart burn, regurgitation<br />

and dysphagia which had appeared after dissection of<br />

involved lymph nodes along the lesser curvature of the stomach<br />

performed with lateral segmentectomy for liver metastases<br />

from rectal cancer. Esophagogastrofiberscopy showed<br />

grade B esophagitis and small hiatal hernia. Since the symptom<br />

had not been controlled by medical therapy and Nissen<br />

fundoplication could not be indicated in such a post surgical<br />

state, ELGP was performed. Using BARD endoscopic suturing<br />

system (EndoCinchTM), two plications were placed at the<br />

esophagogastric junction (EGJ). The procedure time was<br />

55min. There were no adverse events without a slight chest<br />

pain which disappeared within few days. The symptoms associated<br />

with GER markedly reduced after the treatment. Acid<br />

exposure time and bile reflux time were improved after the<br />

procedure (pH

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