2005 SAGES Abstracts

ABSTRACTS Friday, April 15, 2005
toneum on renal perfusion and function and to evaluate two
different strategies for fluid management.
Methods: Twelve 30 kg pigs were randomized into two groups:
Group 1: maintenance (3cc/kg/hr of NaCl) and Group 2: Bolus
(15cc/kg/hr and a 20cc/kg NaCl bolus prior to induction of
pneumoperitoneum). Pigs were studied in a blinded fashion
for 30 minutes prior, 60 minutes during and 30 minutes after
release of 15 mmHg CO2 pneumoperitoneum. Renal cortical
perfusion (RCP) was measured using a laser doppler probe
placed on the right kidney. Renal function was assessed using
the fractional excretion of sodium (FeNa). Data are expressed
as means (SD). Statistical analysis was done with ANOVA.
(*p 30 minutes), whereas rapidly resolved in CO2 group
(within 15 minutes). Parietal blood flow decreased in both
groups (AIR group; 340.5 ?} 48.3 perfusion unit (PU) to 203.2 ?}
26.1 PU, CO2 group; 381.0 ?} 35.1 PU to 181.0 ?} 27.6 PU), however,
recovered within 5 minutes in CO2 group. 2) Continuous
insufflation: during 5-mmHg insufflation, blood flow decreased
in AIR group (404.8 ?} 15.5 PU to 253.1 ?} 14.1 PU; p = 0.0045),
whereas significantly increased in early phase of insufflation in
CO2 group (410.1 ?} 25.3 PU to 484.2 ?} 28.7 PU; p = 0.0487).
Blood flow decreased in both groups during 15-mmHg insufflation,
however, the decrease was still less in CO2 group (AIR
group; 464.4 ?} 61.3 PU to 218.5 ?} 39.3 PU, CO2 group; 408.7
?} 21.4 PU to 365.2 ?} 29.4 PU) (p = 0.0034). In 30-mmHg insufflation,
blood flow decreased and difference was no longer
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