Research Report 2000 - MDC

Foreword
Introduction
Genetics, Bioinformatics and
Structural Biology
Cell Growth and Differentiation
2
Content
• Molecular Biology and Genetics of
Cardiovascular Diseases
Detlev Ganten 20
• Molecular Biology of Peptide Hormones Michael Bader 22
• Genome Research, Gene Variation, and
Complex Disease
Margret Hoehe 24
• Etiology and Pathogenesis of
Hypertension and Vascular Disease
Friedrich C. Luft 26
• Gene Mapping and Identification
in Monogenic and Complex Diseases
André Reis 28
• Tumor Genetics Siegfried Scherneck 30
• Clinical and Molecular Genetics
of Cardiovascular Diseases
Herbert Schuster 33
• Mouse Genetics Carmen Birchmeier 36
• Developmental Genetics Andreas Schedl 38
• Lipids and Experimental Gene Therapy Thomas E. Willnow 40
• Bioinformatics Jens Reich, Peer Bork 42
• Interactions of Biopolymers in Solution Joachim Behlke 44
• Folding and Misfolding of Proteins Gregor Damaschun 46
• Protein Folding and Misfolding Heinz Fabian 48
• Structural Studies of Proteins and
Nucleic Acids by X-ray Crystallography
Udo Heinemann 50
• Role of Protein Dynamics
in Enzyme Function
Christiane Jung 53
• Modeling Nucleic Acid Structure
and Recognition by Proteins
Heinz Sklenar 55
• Conformation, Stability and Interaction
of Biological Macromolecules
Heinz Welfle 57
• Protein Structure Analysis and Proteome
Research
Brigitte Wittmann-Liebold 59
• Growth Control and Gene Regulation
in the Hematopoietic System
Achim Leutz 64
• Regulation of Transcription
in Mammalian Cells
Claus Scheidereit 67
• Differentiation and Growth Control
in Lymphocyte Development and Function
Martin Lipp 69
• Mechanisms Controlling the Initiation
of DNA Replication
Manfred Gossen 72
• Cell Cycle Regulation Hans-Dieter Royer 73
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18
62