RNAO BPG Pressure Ulcers Stage I to IV - Faculty of Health ...

Nursing Best Practice GuidelineAppendix P: Wound Care Cleansing SolutionsSource: Sibbald, Orsted et al. (2006). Reprinted with permission.Cleansing SolutionsAgentSodium hypochlorite solutionHydrogen peroxideMercuric chloride, crystalviolet, ProflavineCetrimide (quarternaryammonium)ChlorhexidineAcetic acid (0.5% to 5%)Povidone iodineEffectsHigh pH causes irritation to skin. Dakins Solution and Eusol (buffered preparation)can select out gram-negative micro-organisms.De-sloughing agent while effervescing. Can harm healthy granulation tissue and mayform air emboli if packed in deep tissue.Bacteriostatic agents active against Gram-positive species only. May be mutagensand can have systemic toxicity.Good detergent, active against Gram-positive and –negative organisms, but hightoxicity to tissue.Active against gram-positive and -negative organisms, with small effect on tissue.Low pH, effective against Pseudomonas species, may select out S. aureus.Broad spectrum of activity, although decreased in the presence of pus or exudates.Toxic with prolonged use or over large areas.101