Assessment & Management <strong>of</strong> <strong>Stage</strong> I <strong>to</strong> <strong>IV</strong> <strong>Pressure</strong> <strong>Ulcers</strong>Discussion <strong>of</strong> EvidenceDebridement is the removal <strong>of</strong> necrotic or devitalized tissue that interferes with wound healing. Theremoval <strong>of</strong> this tissue alters the healing environment <strong>of</strong> a wound by decreasing bacterial concentration anddecreasing the risk <strong>of</strong> the spread <strong>of</strong> infection (AHCPR, 1994; Compliance Network Physicians, 1999; Consortium forSpinal Cord Medicine, 2000; Maklebust & Sieggreen, 1996). Choice <strong>of</strong> specific debridement method(s) should bedetermined by the client’s clinical condition, and includes the client and caregiver’s preferences. Otherfac<strong>to</strong>rs <strong>to</strong> consider are the type, quality, depth and location <strong>of</strong> the necrotic tissue. A distinction needs <strong>to</strong> bemade between surface and deeper-lying necrotic tissue (AHCPR, 1994; Compliance Network Physicians, 1999;Consortium for Spinal Cord Medicine, 2000). It is preferable <strong>to</strong> remove devitalized tissue as quickly as possible,however, the clinical circumstances will impact on the method chosen (Consortium for Spinal Cord Medicine,2000). The general categories <strong>of</strong> debridement are: sharp (or surgical), enzymatic, au<strong>to</strong>lytic, biologic andmechanical. Refer <strong>to</strong> Appendix L for a description <strong>of</strong> key fac<strong>to</strong>rs in deciding on a method <strong>of</strong> debridement.Sharp debridement removes necrotic tissue through the use <strong>of</strong> a scalpel, scissor or other sharp instrument.This is a high-risk procedure!Debridement with a scalpel should be undertaken with caution and performed by speciallytrained and experienced health care pr<strong>of</strong>essionals. Subcutaneous debridement with ascalpel is a controlled act that must be carried out by a physician or the delegate.The advantages <strong>of</strong> this method are the immediate effect and the rapid response <strong>to</strong> the risk <strong>of</strong> infection(Compliance Network Physicians, 1999). Therefore, it is the preferred method for the treatment <strong>of</strong> advancingcellulitis or sepsis, as it quickly removes the source <strong>of</strong> infection. However, it does cause bleeding, mayrequire an anesthetic (for surgical debridement <strong>of</strong> <strong>Stage</strong> <strong>IV</strong> wounds), and has the potential <strong>to</strong> cause injury<strong>to</strong> nervous or other viable tissue (AHCPR, 1994; Compliance Network Physicians, 1999; Consortium for Spinal CordMedicine, 2000; Maklebust & Sieggreen, 1996).The use <strong>of</strong> sterile instruments <strong>to</strong> debride pressure ulcers was recommended by the AHCPR panel (1994)and was further supported by Krasner (1999) in her review <strong>of</strong> the recommendations. There were norandomized controlled trials identified in the literature related <strong>to</strong> the use <strong>of</strong> sterile versus non-sterileinstruments <strong>to</strong> debride pressure ulcers. This recommendation is supported by the general rules <strong>of</strong> surgicalasepsis (Krasner, 1999).Enzymatic debridement is a slower method, and useful for those not appropriate for surgical debridement,those in long-term care facilities, those receiving home care and where ulcer infection is not evident (AHCPR,1994; Consortium for Spinal Cord Medicine, 2000).Au<strong>to</strong>lytic debridement is slow, and should not be utilized on infected ulcers (AHCPR, 1994; Compliance NetworkPhysicians, 1999; Consortium for Spinal Cord Medicine, 2000). It may be prudent <strong>to</strong> avoid all occlusive dressings ifanaerobic infection is suspected or cultured, as occlusive dressings are thought <strong>to</strong> promote an anaerobicenvironment (CREST, 1998).36
Nursing Best Practice GuidelineBiological debridement involves the use <strong>of</strong> sterile larvae <strong>of</strong> Lucilia seicata (greenbottle fly) <strong>to</strong> digestnecrotic tissue from the wound bed. Supported by recent studies, this therapy is gaining popularity but hasstill yet <strong>to</strong> find general acceptance in Canada (Sibbald, Orsted et al., 2006).Mechanical debridement includes the use <strong>of</strong> wet-<strong>to</strong>-dry dressings at specific intervals, hydrotherapy(whirlpool) and wound irrigation. All <strong>of</strong> these methods can be utilized alone, or in preparation for surgical(sharp) debridement (AHCPR, 1994). Mechanical debridement is a slow process, can be painful and shouldbe discontinued when necrotic tissue has been removed (Consortium for Spinal Cord Medicine, 2000). Wet-<strong>to</strong>-drydressings in particular are nonselective in that they remove both viable and necrotic tissue, and arepotentially damaging <strong>to</strong> granulation and epithelial tissue. It is important <strong>to</strong> ensure that appropriate andadequate pain management is incorporated in<strong>to</strong> the plan <strong>of</strong> care when this method is utilized (AHCPR, 1994;Maklebust & Sieggreen, 1996; Oving<strong>to</strong>n, 2002).Control Bacteria/InfectionRecommendation 3.3aThe treatment <strong>of</strong> infection is managed by wound cleansing, systemic antibiotics anddebridement, as needed.Level <strong>of</strong> Evidence – IbRecommendation 3.3bProtect pressure ulcers from sources <strong>of</strong> contamination, e.g., fecal matter.Level <strong>of</strong> Evidence – IIaRecommendation 3.3cFollow Body Substance Precautions (BSP) or an equivalent pro<strong>to</strong>col appropriate for the healthcaresetting and the client’s condition when treating pressure ulcers.Level <strong>of</strong> Evidence – <strong>IV</strong>Recommendation 3.3dMedical management may include initiating a two-week trial <strong>of</strong> <strong>to</strong>pical antibiotics for cleanpressure ulcers that are not healing or are continuing <strong>to</strong> produce exudate after two <strong>to</strong> four weeks <strong>of</strong>optimal patient care. The antibiotic should be effective against gram-negative, gram-positive andanaerobic organisms.Level <strong>of</strong> Evidence – IbRecommendation 3.3eMedical management may include appropriate systemic antibiotic therapy for patients withbacteremia, sepsis, advancing cellulitis or osteomyelitis.Level <strong>of</strong> Evidence – Ib37