Assessment & Management <strong>of</strong> <strong>Stage</strong> I <strong>to</strong> <strong>IV</strong> <strong>Pressure</strong> <strong>Ulcers</strong><strong>Stage</strong> II: Partial thickness loss <strong>of</strong> dermis presenting as a shallow open ulcer with a red pink woundbed, without slough. May also present as an intact or open/ruptured serum-filled blister.<strong>Stage</strong> III: Full thickness tissue loss. Subcutaneous fat may be visible but bone, tendon or muscle arenot exposed. Slough may be present but does not obscure the depth <strong>of</strong> tissue loss. May includeundermining and tunneling.<strong>Stage</strong> <strong>IV</strong>: Full thickness tissue loss with exposed bone, tendon or muscle. Slough or eschar may bepresent on some parts <strong>of</strong> the wound bed. Often includes undermining and tunneling.Unstageable: Full thickness tissue loss in which the base <strong>of</strong> the ulcer is covered by slough (yellow, tan,gray, green or brown) and/or eschar (tan, brown or black) in the wound bed.Reverse Staging <strong>of</strong> <strong>Pressure</strong> <strong>Ulcers</strong>: As adopted by the NPUAP (2000) and the AHCPRguideline (1994), pressure ulcer staging describes the depth <strong>of</strong> tissue involvement in a unilateraldimension <strong>of</strong> deterioration. When pressure ulcers heal, they do not regenerate the same lost tissue.The wound heals with granulation tissue composed <strong>of</strong> endothelial cells, fibroblasts, collagen and anextracellular matrix. Therefore, <strong>to</strong> describe a healing pressure ulcer by using the staging <strong>of</strong> I <strong>to</strong> <strong>IV</strong> inreverse order is incorrect. The guideline development panel, therefore, recommends that reversestaging not be used <strong>to</strong> describe the healing process <strong>of</strong> a wound.Stakeholder: A stakeholder is an individual, group or organization with a vested interest in thedecisions and actions <strong>of</strong> organizations who may attempt <strong>to</strong> influence decisions and actions (Baker,Ogden, Prapaipanich, Keith, Beattie, & Nickleson, 1999). Stakeholders include all individuals or groups who willbe directly or indirectly affected by the change or solution <strong>to</strong> the problem. Stakeholders can be <strong>of</strong>various types, and can be divided in<strong>to</strong> opponents, supporters and neutrals (Ontario Public <strong>Health</strong>Association, 1996).Systematic Review: Application <strong>of</strong> a rigorous scientific approach <strong>to</strong> the preparation <strong>of</strong> a reviewarticle (National <strong>Health</strong> and Medical Research Centre, 1998). Systematic reviews establish where the effects <strong>of</strong>healthcare are consistent and research results can be applied across populations, settings anddifferences in treatment (e.g., dose); and where effects may vary significantly. The use <strong>of</strong> explicit,systematic methods in reviews limits bias (systematic errors) and reduces chance effects, thus providingmore reliable results upon which <strong>to</strong> draw conclusions and make decisions (Clarke & Oxman, 1999).22
Nursing Best Practice GuidelineWound Healing: A cascade <strong>of</strong> events <strong>of</strong> the biologic and immunologic system (CREST, 1998b). Therecognized end point in healing is <strong>to</strong>tal wound closure (Robson, Maggi, Smith, Wasserman, Mosiello, Hill et al., 1999).■Acute wounds: Proceed normally through the repair process from injury <strong>to</strong> healing.■ Chronic wounds: Indolent and fail <strong>to</strong> heal in a timely and orderly process (Waldrop & Doughty, 2000).Viability <strong>of</strong> tissue will determine the course and quality <strong>of</strong> healing (West & Gimbel, 2000).Wound Healing (Phases): The wound healing response can be divided in<strong>to</strong> distinct bu<strong>to</strong>verlapping phases:HEMOSTASIS: Protects the body from excessive blood loss and increased exposure<strong>to</strong> bacterial contamination.■ Vasoconstriction controls blood loss.■ Vasodilation and increase <strong>of</strong> capillary permeability <strong>to</strong> leukocytes and platelets.■ Formation <strong>of</strong> clot.INFLAMMATION: Prepares wound bed for healing by natural au<strong>to</strong>lysis.■ Disintegration or liquefaction <strong>of</strong> tissue or cells by leukocytes and enzymes.PROLIFERATION: Filling in and coverage <strong>of</strong> the wound bed.■ Neoangiogenesis is the production <strong>of</strong> a capillary and arteriole network.■■■Granulation is the development <strong>of</strong> connective tissue.Contraction is the mobilizing force <strong>of</strong> pulling the wound edges <strong>to</strong>gether.Epithelialization is the resurfacing and closure <strong>of</strong> the wound.REMODELLING: Maturation <strong>of</strong> the wound.■ Tensile strength <strong>of</strong> the scar tissue increases <strong>to</strong> not more than 80% <strong>of</strong> the tensile strength<strong>of</strong> non-wounded tissue.23